A tale of two pili: assembly and function of pili in bacteria.

A tale of two pili: assembly and function of pili in bacteria.
复制标题

DOI:
10.1016/j.tim.2010.03.002
复制
发表时间:
2010-05
影响因子:
15.9
通讯作者:
Hultgren SJ
Hultgren SJ
中科院分区:
生物学1区
文献类型:
--
作者:
Kline KA;Dodson KW;Caparon MG;Hultgren SJ

文献摘要

参考文献

被引文献

相似文献

长期以来,细菌皮利被认为是革兰氏阴性细菌疾病进展中重要的初始宿主-病原体相互作用的介质。对革兰氏阳性菌的皮利在毒力中的作用以及其生物发生的独特性质的认识是一个迅速兴起的研究领域。在这篇综述中,我们专注于最近的进展之一,研究时间最长的革兰氏阴性菌菌毛系统,伴侣/引导组装皮利,沿着新人的领域,分选酶组装的皮利的革兰氏阳性菌。在这两个系统中,最近出现了大量新的结构和分子细节。有鉴于此,我们探索分子伴侣/引座员和分选酶组装菌毛生物发生之间的相似之处,并突出每个系统独特的范例,着眼于使用每个系统的知识提出新的问题,并为其他未来的研究提供信息。
Bacterial pili have long been recognized as mediators of initial host-pathogen interactions important for the progression of Gram-negative bacterial diseases. An appreciation for the role of pili on Gram-positive bacteria in virulence, as well as the unique properties of their biogenesis is a rapidly emerging area of research. In this review, we focus on recent advances in one of the longest-studied Gram-negative pilus systems, the chaperone/usher assembled pili, along with the newcomer to the field, the sortase-assembled pili of Gram-positive bacteria. In both systems, a wealth of new structural and molecular details has emerged recently. In light of this, we explore similarities between chaperone/usher and sortase-assembled pilus biogenesis and highlight paradigms unique to each, with an eye toward using knowledge of each system to raise new questions and inform future studies of the other.
革兰氏阴性细菌中非flagellar蛋白附加的结构和生物发生。
DOI: 10.1038/emboj.2008.155
发表时间: 2008-09-03
期刊: EMBO JOURNAL
影响因子: 11.4
作者:
Fronzes, Remi;Remaut, Han;Waksman, Gabriel
通讯作者: Waksman, Gabriel
DOI: 10.1002/path.1700700210
发表时间: 1955-01-01
期刊: JOURNAL OF PATHOLOGY AND BACTERIOLOGY
影响因子: --
作者:
DUGUID, JP;SMITH, IW;EDMUNDS, PN
通讯作者: EDMUNDS, PN
DOI: 10.1111/j.1365-2958.2008.06220.x
发表时间: 2008-06-01
影响因子: 3.6
作者:
Edwards, Andrew M.;Manetti, Andrea G. O.;Grandi, Guido
通讯作者: Grandi, Guido
DOI: 10.1016/0092-8674(87)90565-4
发表时间: 1987-04-24
期刊: CELL
影响因子: 64.5
作者:
BAGA, M;NORGREN, M;NORMARK, S
通讯作者: NORMARK, S
DOI: 10.1073/pnas.0511017103
发表时间: 2006-02-21
影响因子: 11.1
作者:
Barocchi, MA;Rie, J;Henriques-Normark, B
通讯作者: Henriques-Normark, B