Genetic Features of Reproductive Traits in Bovine and Buffalo: Lessons From Bovine to Buffalo.
Genetic Features of Reproductive Traits in Bovine and Buffalo: Lessons From Bovine to Buffalo.
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牛和水牛繁殖性状的遗传特征：从牛到水牛的教训
DOI：
10.3389/fgene.2021.617128
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发表时间：
2021
影响因子：
3.7
通讯作者：
Hua G
中科院分区：
文献类型：
--
作者：
Shao B;Sun H;Ahmad MJ;Ghanem N;Abdel-Shafy H;Du C;Deng T;Mansoor S;Zhou Y;Yang Y;Zhang S;Yang L;Hua G
牛和布法罗是重要的牲畜物种，1000多年来一直为人类生活做出贡献。提高生育力对降低生产成本非常重要。在目前的综述中，我们将生殖性状分为三类：排卵，繁殖和产犊相关性状。系统总结了牛和布法罗繁殖性状的遗传力估计、分子标记和基因组选择等方面的研究进展。本文综述了与牛和水牛繁殖性状相关的遗传力和全基因组关联（GWASs）研究，并试图强调可能有利于布法罗育种的学科。繁殖性状的遗传力估计值为0 ~ 0.57，群体间差异较大。对于某些特定性状，如青春期年龄（AOP）和产犊困难度（CD），大多数肉牛群体表现出相对较高的遗传力。与牛相比，布法罗繁殖性状的遗传研究仅限于初产年龄和产犊间隔性状。利用候选基因法和GWASs筛选和鉴定了与牛繁殖性状相关的多个数量性状位点、候选基因和SNPs。IGF 1和LEP途径除了非编码RNA外，由于其与生殖性状的重要相关性而突出显示。与各性状相关的QTL分布存在较大差异。到目前为止，很少有GWAS在布法罗的年龄在第一次产犊，产犊间隔，和天开放性状。此外，本文还对牛和布法罗繁殖性状的GS研究进行了总结，并对不同报道的准确性进行了比较。综合考虑，GWAS和候选基因方法可以帮助理解复杂性状的分子遗传机制。近年来，遗传相似性被广泛应用，可以对多个性状进行遗传相似性分析，以提高预测的准确性，即使是遗传力较低的性状，也可以与多组学相结合进行进一步分析。
Bovine and buffalo are important livestock species that have contributed to human lives for more than 1000 years. Improving fertility is very important to reduce the cost of production. In the current review, we classified reproductive traits into three categories: ovulation, breeding, and calving related traits. We systematically summarized the heritability estimates, molecular markers, and genomic selection (GS) for reproductive traits of bovine and buffalo. This review aimed to compile the heritability and genome-wide association studies (GWASs) related to reproductive traits in both bovine and buffalos and tried to highlight the possible disciplines which should benefit buffalo breeding. The estimates of heritability of reproductive traits ranged were from 0 to 0.57 and there were wide differences between the populations. For some specific traits, such as age of puberty (AOP) and calving difficulty (CD), the majority beef population presents relatively higher heritability than dairy cattle. Compared to bovine, genetic studies for buffalo reproductive traits are limited for age at first calving and calving interval traits. Several quantitative trait loci (QTLs), candidate genes, and SNPs associated with bovine reproductive traits were screened and identified by candidate gene methods and/or GWASs. The IGF1 and LEP pathways in addition to non-coding RNAs are highlighted due to their crucial relevance with reproductive traits. The distribution of QTLs related to various traits showed a great differences. Few GWAS have been performed so far on buffalo age at first calving, calving interval, and days open traits. In addition, we summarized the GS studies on bovine and buffalo reproductive traits and compared the accuracy between different reports. Taken together, GWAS and candidate gene approaches can help to understand the molecular genetic mechanisms of complex traits. Recently, GS has been used extensively and can be performed on multiple traits to improve the accuracy of prediction even for traits with low heritability, and can be combined with multi-omics for further analysis.
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影响因子：
2.9
作者：
Cochran SD;Cole JB;Null DJ;Hansen PJ
通讯作者：
Hansen PJ
影响因子：
1.8
作者：
Abdel-Shafy, Hamdy;Awad, Mohamed A. A.;Abou-Bakr, Samy
通讯作者：
Abou-Bakr, Samy
影响因子：
3.3
作者：
Allan, M. F.;Thallman, R. M.;Smith, T. P. L.
通讯作者：
Smith, T. P. L.
影响因子：
3.6
作者：
Berry, D. P.;Wall, E.;Pryce, J. E.
通讯作者：
Pryce, J. E.
影响因子：
0.9
作者：
BARROS, CAMILA DA COSTA;ASPILCUETA-BORQUIS, RÚSBEL RAUL;TONHATI, HUMBERTO
通讯作者：
TONHATI, HUMBERTO