COVID-KOP: integrating emerging COVID-19 data with the ROBOKOP database.
COVID-KOP: integrating emerging COVID-19 data with the ROBOKOP database.
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DOI:
10.1093/bioinformatics/btaa718
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发表时间:
2021-05-01
期刊:
影响因子:
--
通讯作者:
Tropsha A
中科院分区:
文献类型:
--
作者:
Korn D;Bobrowski T;Li M;Kebede Y;Wang P;Owen P;Vaidya G;Muratov E;Chirkova R;Bizon C;Tropsha A
In response to the COVID-19 pandemic, we established COVID-KOP, a new knowledgebase integrating the existing Reasoning Over Biomedical Objects linked in Knowledge Oriented Pathways (ROBOKOP) biomedical knowledge graph with information from recent biomedical literature on COVID-19 annotated in the CORD-19 collection. COVID-KOP can be used effectively to generate new hypotheses concerning repurposing of known drugs and clinical drug candidates against COVID-19 by establishing respective confirmatory pathways of drug action. COVID-KOP is freely accessible at https://covidkop.renci.org/. For code and instructions for the original ROBOKOP, see: https://github.com/NCATS-Gamma/robokop.
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