Sustained complete remission of primary effusion lymphoma with adjunctive ganciclovir treatment in an HIV-positive patient
Sustained complete remission of primary effusion lymphoma with adjunctive ganciclovir treatment in an HIV-positive patient
复制标题
HIV 阳性患者接受更昔洛韦辅助治疗，原发性渗出性淋巴瘤持续完全缓解
作者：
R. Pereira;J. Carvalho;C. Patrício;P. Farinha
Primary effusion lymphoma (PEL) is one of the least common of the AIDS-related lymphomas, accounting for less than 1–4% of cases. Clinical manifestations depend on the extent and distribution of disease and, as in the majority of patients no detectable mass lesion is found, symptoms are related to fluid accumulation, dyspnoea (pleural or pericardial effusions), abdominal distension (ascites) or joint swelling. The median survival after diagnosis, even with aggressive chemotherapy, remains poor and remissions are often of short duration. We present the case of a 31-year-old man with AIDS and diagnosis of PEL, in whom sustained and complete remission of the tumour was achieved with adjunctive ganciclovir therapy. Since the disease is so uncommon, there is a paucity of data to guide the treatment of these patients; ganciclovir might be a potential antiviral therapeutic option, as demonstrated by the 2-year remission achieved in our patient.
影响因子：
20.3
作者：
Bhatt, Shruti;Ashlock, Brittany M.;Lossos, Izidore S.
通讯作者：
Lossos, Izidore S.
DOI：
10.1086/592298
发表时间：
2008-11-01
期刊：
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子：
--
作者：
Sullivan RJ;Pantanowitz L;Casper C;Stebbing J;Dezube BJ
通讯作者：
Dezube BJ
影响因子：
9.7
作者：
Wen, Kwun Wah;Damania, Blossom
通讯作者：
Damania, Blossom