The antigenic determinants of most of the proteins coded by the three serotypes of reovirus are highly conserved during evolution.
The antigenic determinants of most of the proteins coded by the three serotypes of reovirus are highly conserved during evolution.
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呼肠孤病毒三种血清型编码的大多数蛋白质的抗原决定簇在进化过程中高度保守。
DOI:
10.1016/0042-6822(80)90321-9
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发表时间:
1980
期刊:
影响因子:
3.7
通讯作者:
Joklik,WK
中科院分区:
文献类型:
--
作者:
Gaillard,RK;Joklik,WK
The antigenic relationships of the proteins encoded by strains of the three reovirus serotypes were assessed by measuring the efficiency with which they were precipitated from infected cell extracts by antisera against the three serotypes. While the antigenic determinants on some proteins, particularly those on the minor outer capsid shell component σ-1, display type-specificity, the antigenic determinants on most cognate proteins encoded by the three serotypes are very similar. This is true even for the proteins of serotype 2, the genome of which is related to those of serotypes 1 and 3 by no more than 10% as judged by RNA-RNA hybridization. The results indicate that the antigenic determinants on most of the proteins of the three reovirus serotypes have been highly conserved during evolution.
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影响因子:
4.6
作者:
H. Martinson;L. Lewandowski
通讯作者:
L. Lewandowski
影响因子:
3.7
作者:
SMITH, RE;ZWEERINK, HJ;JOKLIK, WK
通讯作者:
JOKLIK, WK
影响因子:
3.7
作者:
Li,JK;Keene,JD;Scheible,PP;Joklik,WK
通讯作者:
Joklik,WK
影响因子:
3.7
作者:
H. Zweerink;W. Joklik
通讯作者:
H. Zweerink;W. Joklik
影响因子:
4.4
作者:
S. Kessler
通讯作者:
S. Kessler