The antigenic determinants of most of the proteins coded by the three serotypes of reovirus are highly conserved during evolution.

The antigenic determinants of most of the proteins coded by the three serotypes of reovirus are highly conserved during evolution.
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呼肠孤病毒三种血清型编码的大多数蛋白质的抗原决定簇在进化过程中高度保守。

DOI:
10.1016/0042-6822(80)90321-9
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发表时间:
1980
期刊:
影响因子:
3.7
通讯作者:
Joklik,WK
Joklik,WK
中科院分区:
医学3区
文献类型:
--
作者:
Gaillard,RK;Joklik,WK

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三种呼肠孤病毒血清型菌株编码的蛋白的抗原关系通过测定抗血清对三种血清型的感染细胞提取物的沉淀效率来评估。虽然某些蛋白上的抗原决定因子,特别是次要的外衣壳组分σ-1上的抗原决定因子具有类型特异性,但三种血清型编码的大多数同源蛋白上的抗原决定因子非常相似。即使是血清型2的蛋白质也是如此,根据RNA-RNA杂交判断,血清型2的基因组与血清型1和3的相关性不超过10%。结果表明,三种呼肠孤病毒血清型中大部分蛋白的抗原决定因子在进化过程中高度保守。
The antigenic relationships of the proteins encoded by strains of the three reovirus serotypes were assessed by measuring the efficiency with which they were precipitated from infected cell extracts by antisera against the three serotypes. While the antigenic determinants on some proteins, particularly those on the minor outer capsid shell component σ-1, display type-specificity, the antigenic determinants on most cognate proteins encoded by the three serotypes are very similar. This is true even for the proteins of serotype 2, the genome of which is related to those of serotypes 1 and 3 by no more than 10% as judged by RNA-RNA hybridization. The results indicate that the antigenic determinants on most of the proteins of the three reovirus serotypes have been highly conserved during evolution.
胞质多角体病毒、伤口肿瘤病毒和呼肠孤病毒1、2、3株双链RNA基因组之间的序列同源性研究。
DOI: --
发表时间: 1974
期刊: Intervirology
影响因子: 4.6
作者:
H. Martinson;L. Lewandowski
通讯作者: L. Lewandowski
DOI: 10.1016/0042-6822(69)90017-8
发表时间: 1969-01-01
期刊: VIROLOGY
影响因子: 3.7
作者:
SMITH, RE;ZWEERINK, HJ;JOKLIK, WK
通讯作者: JOKLIK, WK
呼肠孤病毒血清型 1、2 和 3 的 S1 基因正链和负链 3 末端序列的性质。
DOI: 10.1016/0042-6822(80)90154-3
发表时间: 1980
期刊: Virology
影响因子: 3.7
作者:
Li,JK;Keene,JD;Scheible,PP;Joklik,WK
通讯作者: Joklik,WK
DOI: 10.1016/0042-6822(70)90171-6
发表时间: 1970-07
期刊: Virology
影响因子: 3.7
作者:
H. Zweerink;W. Joklik
通讯作者: H. Zweerink;W. Joklik
DOI: 10.4049/jimmunol.115.6.1617
发表时间: 1975-12
影响因子: 4.4
作者:
S. Kessler
通讯作者: S. Kessler