The neural code for face memory

The neural code for face memory
复制标题

面部记忆的神经编码

DOI:
10.1101/2021.03.12.435023
复制
发表时间:
2021
期刊:
bioRxiv
影响因子:
--
通讯作者:
Doris Y. Tsao
Doris Y. Tsao
中科院分区:
--
文献类型:
--
作者:
Liang She;M. Benna;Yuelin Shi;Stefano Fusi;Doris Y. Tsao

文献摘要

参考文献

被引文献

相似文献

识别熟悉视觉物体的能力对生存至关重要。神经科学的一个核心假设是,长期记忆是由编码感官刺激的相同大脑区域代表的(1)。下颞叶(IT)皮层中的神经元使用分布式轴编码来表示视觉对象的感觉感受(2-4)。同样的IT神经群是否以及如何代表视觉对象的长期记忆仍然不清楚。在这里,我们研究了熟悉的面孔是如何编码在面部补丁AM和嗅周皮层。我们发现,熟悉的面孔在一个不同的子空间从陌生的面孔。在短潜伏期内,熟悉面孔子空间相对于不熟悉面孔子空间发生位移,然后在长潜伏期内发生扭曲,以增加熟悉面孔之间的神经距离。这种扭曲使得在AM和PR中对熟悉面孔的辨别能力显著提高。PR的失活并不影响AM中的这些记忆痕迹,这表明记忆痕迹来自IT皮质内的内在复发过程或与内侧颞叶外的下游区域的相互作用(5,6)。总的来说,我们的研究结果表明,熟悉面孔的记忆在IT和嗅周皮层中由一个独特的长潜伏期代码表示,该代码被优化以区分熟悉的身份。
The ability to recognize familiar visual objects is critical to survival. A central assumption of neuroscience is that long-term memories are represented by the same brain areas that encode sensory stimuli (1). Neurons in inferotemporal (IT) cortex represent the sensory percept of visual objects using a distributed axis code (2–4). Whether and how the same IT neural population represents the long-term memory of visual objects remains unclear. Here, we examined how familiar faces are encoded in face patch AM and perirhinal cortex. We found that familiar faces were represented in a distinct subspace from unfamiliar faces. The familiar face subspace was shifted relative to the unfamiliar face subspace at short latency and then distorted to increase neural distances between familiar faces at long latency. This distortion enabled markedly improved discrimination of familiar faces in both AM and PR. Inactivation of PR did not affect these memory traces in AM, suggesting that the memory traces arise from intrinsic recurrent processes within IT cortex or interactions with downstream regions outside the medial temporal lobe (5, 6). Overall, our results reveal that memories of familiar faces are represented in IT and perirhinal cortex by a distinct long-latency code that is optimized to distinguish familiar identities.
DOI: 10.3758/s13428-014-0532-5
发表时间: 2015-12-01
影响因子: 5.4
作者:
Ma, Debbie S.;Correll, Joshua;Wittenbrink, Bernd
通讯作者: Wittenbrink, Bernd
DOI: 10.1364/josaa.20.001434
发表时间: 2003-07-01
影响因子: 1.9
作者:
Lee, TS;Mumford, D
通讯作者: Mumford, D
DOI: --
发表时间: --
期刊: --
影响因子: --
作者:
A R Simard;D. Soulet;G. Gowing;J. P. Julien;S. Rivest;B Ajami;J. L. Bennett;C. Krieger;W. Tetzlaff;F. M. Rossi;S. P. Sorokin;R. F. Hoyt;D. G. Blunt;N. McNelly;G. Hoeffel;X. H. Zong;R. Basu;H. Ketchum;W. Freiwald;Doris Y. Tsao
通讯作者: A R Simard;D. Soulet;G. Gowing;J. P. Julien;S. Rivest;B Ajami;J. L. Bennett;C. Krieger;W. Tetzlaff;F. M. Rossi;S. P. Sorokin;R. F. Hoyt;D. G. Blunt;N. McNelly;G. Hoeffel;X. H. Zong;R. Basu;H. Ketchum;W. Freiwald;Doris Y. Tsao
DOI: 10.1093/cercor/bhn015
发表时间: 2008-11-01
期刊: CEREBRAL CORTEX
影响因子: 3.7
作者:
Anderson, Britt;Mruczek, Ryan E. B.;Sheinberg, David
通讯作者: Sheinberg, David
DOI: 10.1523/jneurosci.19-01-00431.1999
发表时间: 1999-01-01
影响因子: 5.3
作者:
McAdams, CJ;Maunsell, JHR
通讯作者: Maunsell, JHR