Performance characteristics of the measurement of gastric volume using single photon emission computed tomography.
Performance characteristics of the measurement of gastric volume using single photon emission computed tomography.
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DOI：
10.1111/j.1365-2982.2010.01660.x
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发表时间：
2011-04
影响因子：
3.5
通讯作者：
Zinsmeister AR
中科院分区：
文献类型：
--
作者：
Breen M;Camilleri M;Burton D;Zinsmeister AR
一种非侵入性的单光子发射计算机断层扫描（SPECT）方法的开发和验证，以测量胃容积（GV）。胃容积反应的自然变化和SPECT成像的性能特征尚不清楚。我们的主要目的是评估SPECT成像的性能特征，通过估计过去十年中433名参与者的空腹和餐后GV的个体间变异系数（COV），以及至少接受过2项研究的所有志愿者的个体内COV。第二个目的是评估性别、BMI和年龄对GV的关系。研究中所有受试者（n=433）的COVINTER为32.6%空腹、16.0%进食和19.0% Δ进食-空腹。47例重复估计胃容量的受试者的COVINTRA为37.0%空腹、17.6%进食和22.0% Δ进食-空腹。COVINTRA在2至60个月的时间间隔内保持稳定。性别或亚组之间无显著差异。平均进食量和胃调节量与年龄和BMI相关，但可归因的变化幅度<5%。SPECT测量GV的COVINTRA和COVINTER非常相似，年龄和BMI的影响较小。这些数据是重要的计划未来的研究GV和进一步验证SPECT的胃动力障碍和肥胖的研究。
A noninvasive single photon emission computed tomography (SPECT) method was developed and validated to measure gastric volumes (GV). The natural variation in gastric volume responses and performance characteristics of SPECT imaging are unclear. Our primary aim was to assess the performance characteristics of SPECT imaging by estimating the inter-individual coefficients of variation (COV) in fasting and postprandial GV in 433 participants in prior research studies over the last decade, and the intra-individual COV in all volunteers who had undergone at least 2 studies. A second aim was to assess the relationship of gender, BMI and age on GV. The COVINTER for all subjects in the study (n=433) was 32.6% fasting, 16.0% fed, and 19.0 % Δ fed - fasting. The COVINTRA for 47 subjects with repeat estimates of gastric volume was 37.0% fasting, 17.6% fed, and 22.0 % Δ fed - fasting. COVINTRA was stable over time interval from 2 to 60 months. There were no significant differences by gender or subgroups. Mean fed and gastric accommodation volumes were associated with age and BMI but the magnitude of variation attributable was <5%. COVINTRA and COVINTER of GV by SPECT are very similar, and there is a small effect of age and BMI. These data are important for planning future studies of GV and further validate SPECT for studies of gastric motility disorders and obesity.
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影响因子：
3.5
作者：
Fruehauf, H.;Goetze, O.;Fried, M.
通讯作者：
Fried, M.
影响因子：
19.7
作者：
de Zwart, IM;Mearadji, B;Kunz, P
通讯作者：
Kunz, P
DOI：
10.1152/ajpgi.1999.277.6.g1217
发表时间：
1999-12-01
影响因子：
4.5
作者：
Kuiken, SD;Samsom, M;O'Connor, MK
通讯作者：
O'Connor, MK
影响因子：
12.6
作者：
Castillo, Emma Janet;Camilleri, Michael;Zinsmeister, Alan R.
通讯作者：
Zinsmeister, Alan R.
影响因子：
24.5
作者：
Bouras, EP;Delgado-Aros, S;Chial, HJ
通讯作者：
Chial, HJ