Current progress in bioactive ceramic scaffolds for bone repair and regeneration.
Current progress in bioactive ceramic scaffolds for bone repair and regeneration.
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DOI：
10.3390/ijms15034714
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发表时间：
2014-03-18
影响因子：
5.6
通讯作者：
Peng S
中科院分区：
文献类型：
--
作者：
Gao C;Deng Y;Feng P;Mao Z;Li P;Yang B;Deng J;Cao Y;Shuai C;Peng S
在过去的几十年里，生物活性陶瓷因其在刺激细胞增殖、分化和骨组织再生方面的成功而受到极大的关注。它们可以与人体内的细胞和组织反应并形成化学键。本文就生物活性陶瓷在骨修复与再生中的应用作一综述。系统地综述了生物活性陶瓷的类型和特点，纳米结构和层状多孔结构的制备方法，陶瓷支架的典型增韧方法以及相应的增韧机理，如纤维增韧、晶须增韧和颗粒增韧。此外，对陶瓷与细胞之间的相互作用机制以及陶瓷基复合材料的发展也提供了更多的见解。从骨修复和再生的角度讨论了生物活性陶瓷的发展和面临的挑战。
Bioactive ceramics have received great attention in the past decades owing to their success in stimulating cell proliferation, differentiation and bone tissue regeneration. They can react and form chemical bonds with cells and tissues in human body. This paper provides a comprehensive review of the application of bioactive ceramics for bone repair and regeneration. The review systematically summarizes the types and characters of bioactive ceramics, the fabrication methods for nanostructure and hierarchically porous structure, typical toughness methods for ceramic scaffold and corresponding mechanisms such as fiber toughness, whisker toughness and particle toughness. Moreover, greater insights into the mechanisms of interaction between ceramics and cells are provided, as well as the development of ceramic-based composite materials. The development and challenges of bioactive ceramics are also discussed from the perspective of bone repair and regeneration.
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DOI：
10.1152/physiologyonline.2001.16.5.208
发表时间：
2001-10-01
期刊：
NEWS IN PHYSIOLOGICAL SCIENCES
影响因子：
--
作者：
Braddock, M;Houston, P;Ashcroft, P
通讯作者：
Ashcroft, P
影响因子：
3.9
作者：
Ahn, ES;Gleason, NJ;Ying, JY
通讯作者：
Ying, JY
影响因子：
4.5
作者：
CHOKSHI, AH
通讯作者：
CHOKSHI, AH
影响因子：
5
作者：
Fielding, Gary A.;Bandyopadhyay, Amit;Bose, Susmita
通讯作者：
Bose, Susmita
影响因子：
5.6
作者：
Chiara G;Letizia F;Lorenzo F;Edoardo S;Diego S;Stefano S;Eriberto B;Barbara Z
通讯作者：
Barbara Z