Creating a population-averaged standard brain template for Japanese macaques (M. fuscata).

Creating a population-averaged standard brain template for Japanese macaques (M. fuscata).
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DOI:
10.1016/j.neuroimage.2010.05.006
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发表时间:
2010-10-01
期刊:
影响因子:
5.7
通讯作者:
Iriki, A.
Iriki, A.
中科院分区:
医学1区
文献类型:
--
作者:
Quallo, M. M.;Price, C. J.;Ueno, K.;Asamizuya, T.;Cheng, K.;Lemon, R. N.;Iriki, A.

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一些现代数字解剖技术,结构磁共振脑图像的基础上,最近已成为适用于非人类灵长类动物的大脑。这种基于体素的定量技术需要特定物种的标准化大脑模板。在这里,我们提出了一个日本猕猴(Macaca fuscata)的大脑模板。该模板被设计用作将日本猕猴大脑空间标准化为标准空间的工具。虽然这种猕猴被广泛用于神经科学研究,包括对高级认知脑功能的研究,但目前还没有标准的大脑MRI模板。这里提出的模板是基于T1/T2* 加权,高分辨率4 T MR图像从16只成年雄性日本猕猴。T1/T2* 图像用于校正由于使用表面线圈而导致的信号不均衡。基于这些图像,为灰质、白色物质和脑脊液创建群体平均概率图。这里提出的新模板应该有助于未来使用日本猕猴进行大脑研究。全脑模板可在http://brainatlas.brain.riken.jp/jm/modules/xoonips/listitem.php?上获得index_id=9。
A number of modern digital anatomy techniques, based on structural MR brain images, have recently become applicable to the non-human primate brain. Such voxel-based quantitative techniques require a species-specific standardized brain template. Here we present a brain template for the Japanese macaque (Macaca fuscata). The template was designed to be used as a tool for spatially normalising Japanese macaque brains into a standard space. Although this species of macaque monkey is widely used in neuroscience research, including studies of higher cognitive brain functions, no standard MRI template of its brain is presently available. The template presented here is based on T1/T2* weighted, high-resolution 4 T MR images obtained from 16 male adult Japanese macaque monkeys. T1/T2* images were used to correct the signal inequalities resulting from the use of a surface coil. Based on these images, population-averaged probability maps were created for grey matter, white matter and cerebrospinal fluid. The new template presented here should facilitate future brain research using the Japanese macaque monkey. Whole brain templates are available at http://brainatlas.brain.riken.jp/jm/modules/xoonips/listitem.php?index_id=9.
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