Dosage effects and individual responsivity to methylphenidate in attention deficit disorder.

Dosage effects and individual responsivity to methylphenidate in attention deficit disorder.
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注意力缺陷障碍中哌醋甲酯的剂量效应和个体反应。

DOI:
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发表时间:
1988
期刊:
Journal of Child Psychology and Psychiatry and Allied Disciplines
影响因子:
--
通讯作者:
B. Britton
B. Britton
中科院分区:
--
文献类型:
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作者:
V. Douglas;R. Barr;K. Amin;M. O'Neill;B. Britton

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三种剂量的哌甲酯(0.15,0.30和0.60 mg/kg)的影响进行了评估,在19 ADD-H儿童的各种认知,学术和行为的措施,在实验室和教室。在几乎所有的措施中发现了一个主要的线性模式的改善。在一项认知任务中,0.3和0.6 mg/kg之间的轻微下降可能会导致更高剂量降低兴奋剂的有效性或导致某些“高水平/高负荷”任务的减少。个别儿童的反应模式在各项措施中差异很大。所有的孩子都至少在几个方面有所改善。结果被解释为自我调节过程的刺激激活的证据。
Effects of three dosages of methylphenidate (0.15, 0.30 and 0.60 mg/kg) were assessed in 19 ADD-H children on a variety of cognitive, academic and behavioral measures in the laboratory and the classroom. A predominant linear pattern of improvement was found across almost all measures. A slight decrease between 0.3 and 0.6 mg/kg on one cognitive task leaves open the possibility that higher dosages reduce stimulant effectiveness or cause decrements on some kinds of "high-level/high load" tasks. Response patterns of individual children varied considerably across measures. All children improved on at least several measures. Results were interpreted as evidence for stimulant activation of self-regulatory processes.
两种剂量的哌醋甲酯对多动儿童言语信息处理的影响。
DOI: 10.1097/00004714-198404020-00004
发表时间: 1984
影响因子: 2.9
作者:
Peeke,S;Halliday,R;Callaway,E;Prael,R;Reus,V
通讯作者: Reus,V
注意力缺陷障碍儿童的注意力组成、哌醋甲酯剂量和血液水平。
DOI: --
发表时间: 1986
期刊: Pediatrics
影响因子: 8
作者:
Sebrechts,MM;Shaywitz,SE;Shaywitz,BA;Jatlow,P;Anderson,GM;Cohen,DJ
通讯作者: Cohen,DJ
DOI: 10.1111/j.1469-7610.1983.tb00569.x
发表时间: 1983
期刊: Journal of child psychology and psychiatry, and allied disciplines
影响因子: --
作者:
Gittelman,R;Klein,DF;Feingold,I
通讯作者: Feingold,I