Significant changes in VLDL-Triacylglycerol and glucose tolerance in obese subjects following ten days of training

Significant changes in VLDL-Triacylglycerol and glucose tolerance in obese subjects following ten days of training
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训练十天后,肥胖受试者的极低密度脂蛋白三酰甘油和葡萄糖耐量发生显着变化

DOI:
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发表时间:
1998
期刊:
European Journal of Applied Physiology and Occupational Physiology
影响因子:
--
通讯作者:
C. Schumann
C. Schumann
中科院分区:
--
文献类型:
--
作者:
T. Angelopoulos;Rebecca A. Lewis;Thanassis Jamurtas;C. Schumann

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摘要 我们研究了 6 名[年龄 37.2 (2.3) 岁]久坐、肥胖 [BMI 34.4 (3.0) kg · m−2] 且糖耐量正常的男性十天训练对脂质代谢的影响。在10天的训练期之前和结束时进行口服葡萄糖耐量测试。每次每日锻炼的持续时间为40分钟,强度相当于年龄预测最大心率的约75%。在禁食过夜后、第 10 天之前和结束时进行血液测量。运动训练后血浆三酰甘油显着降低(p<0.05)(2.15±0.29 vs. 1.55±0.28mmol··l−1)。极低密度脂蛋白-三酰甘油也显着降低(p<0.05)(1.82±0.3 vs.1.29±0.29mmol·1-1)。训练后没有观察到高密度脂蛋白胆固醇的显着变化。训练后空腹血糖和空腹血浆胰岛素显着降低[血糖:5.9 (0.2) mmol · l−1 vs. 5.3 (0.22) mmol · l−1 (p < 0.05);胰岛素 264.3 (53.8) ρ · mol · l−1 与 200.9 (30.1) ρ · mol · l−1,p = 0.05]。 OGTT 期间葡萄糖曲线下的总面积显着下降 (p<<0.05)。这些初步数据表明,短期运动在不伴随体重损失的情况下,会引起血浆三酰甘油、极低密度脂蛋白三酰甘油和葡萄糖耐量的有利变化,但对高密度脂蛋白胆固醇没有影响。
Abstract We characterized the effect of ten days of training on lipid metabolism in 6 [age 37.2 (2.3) years] sedentary, obese [BMI 34.4 (3.0) kg · m−2] males with normal glucose tolerance. An oral glucose tolerance test was performed prior to and at the end of the 10 d of training period. The duration of each daily exercise session was 40 min at an intensity equivalent to ˜75% of the age predicted maximum heart rate. Blood measurements were performed after an overnight fast, before and at the end of the 10 d period. Plasma triacylglycerol was significantly (p < 0.05) reduced following exercise training (2.15 ± 0.29 vs. 1.55 ± 0.28 mmol · l−1). Very low density lipoprotein-triacylglycerol was also significantly (p < 0.05) reduced (1.82 ± 0.3 vs. 1.29 ± 0.29 mmol · l−1). No significant changes in high density lipoprotein-cholesterol were observed as a result of training. Following training fasting plasma glucose and fasting plasma insulin were significantly reduced [Glucose: 5.9 (0.2) mmol · l−1 vs. 5.3 (0.22) mmol · l−1 (p < 0.05); Insulin 264.3 (53.8) ρ · mol · l−1 vs. 200.9 (30.1) ρ · mol · l−1, p = 0.05]. The total area under the glucose curve during the OGTT decreased significantly (p < 0.05). These preliminary data suggest that short-term exercise, without concomitant loss of body mass, induces favorable changes in plasma triacylglycerol, and very low density lipoprotein-triacylglycerol and glucose tolerance but has no effect on high density lipoproteincholesterol.
运动训练对局部肥胖绝对和相对测量的影响。
DOI: --
发表时间: 1994
期刊: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity
影响因子: --
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7-10 天的自行车测功机运动对骨骼肌 GLUT-4 蛋白含量的影响。
DOI: 10.1152/jappl.1995.79.5.1562
发表时间: 1995
期刊: Journal of applied physiology (Bethesda, Md. : 1985)
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在不减肥的情况下进行体育锻炼会降低空腹和餐后富含甘油三酯的脂蛋白水平。
DOI: 10.1161/01.cir.79.5.1007
发表时间: 1989
期刊: Circulation
影响因子: 37.8
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DOI: 10.1056/nejm199108083250601
发表时间: 1991-08-08
影响因子: 158.5
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通讯作者: HENNEKENS, CH