A comparison of multiple esterases as biomarkers of organophosphate exposure and effect in two earthworm species.
A comparison of multiple esterases as biomarkers of organophosphate exposure and effect in two earthworm species.
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DOI：
10.1007/s00128-011-0236-9
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发表时间：
2011-04
影响因子：
2.7
通讯作者：
Stoskopf, Michael K.
中科院分区：
文献类型：
--
作者：
Henson-Ramsey, Heather;Schneider, Ashley;Stoskopf, Michael K.
以5 μg/cm2的马拉硫磷浓度为研究对象，研究了两种不同种类的蚯蚓——臭爱森蚓（Eisenia fetida）和陆生蚓（Lumbricus terrestris）作为有机磷暴露哨兵的作用，并对三种不同的酯酶作为马拉硫磷暴露的生物标志物及其影响进行了评价。测定每个物种和每种酯酶的组织外源性负荷和酯酶活性，以评估变异性。粪草的组织负荷变异性是陆生草的4倍，其基础酯酶活性变异性较小。试图将马拉硫磷和马拉硫磷的组织负荷与暴露后的酯酶活性联系起来。蚯蚓组织中未发现丙霉酸。通过比较乙酰胆碱酯酶、丁基胆碱酯酶和羧酸酯酶活性与马拉硫磷负荷没有确定显著的相关性。
Two different earthworm species, Eisenia fetida and Lumbricus terrestris, were exposed to 5 μg/cm2 of malathion to evaluate their usefulness as sentinels of organophosphate exposure and to assess three different esterases, as biomarkers of malathion exposure and effect. Tissue xenobiotic burdens and esterase activity were determined for each species and each esterase in order to assess variability. E. fetida exhibited 4-fold less variability in tissue burdens than did L. terrestris and had less variable basal esterase activities. An attempt was made to correlate malathion and malaoxon tissue burdens with esterase activity post-exposure. There was no malaoxon present in the earthworm tissues. No significant correlations were determined by comparing acetylcholinesterase, butyrylcholinesterase, nor carboxylesterase activities with malathion burdens.
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影响因子：
5.8
作者：
ELLMAN, GL;COURTNEY, KD;FEATHERSTONE, RM
通讯作者：
FEATHERSTONE, RM
DOI：
10.1006/faat.1997.2329
发表时间：
1997-08-01
期刊：
FUNDAMENTAL AND APPLIED TOXICOLOGY
影响因子：
--
作者：
Chanda, SM;Mortensen, SR;Padilla, S
通讯作者：
Padilla, S
DOI：
10.1007/s00128-007-9194-7
发表时间：
2007-06-01
影响因子：
2.7
作者：
Henson-Ramsey, H.;Kennedy-Stoskopf, S.;Stoskopf, M. K.
通讯作者：
Stoskopf, M. K.
影响因子：
6.1
作者：
GILMAN, AP;VARDANIS, A
通讯作者：
VARDANIS, A
影响因子：
2.9
作者：
BRADFORD, MM
通讯作者：
BRADFORD, MM