Study on the Anticancer Effects of Plasma-Activated Saline Perfusion Based on a Microfluidic System
Study on the Anticancer Effects of Plasma-Activated Saline Perfusion Based on a Microfluidic System
复制标题
基于微流控系统的等离子体激活盐水灌注的抗癌作用研究
DOI：
10.1007/s11090-022-10297-5
复制
发表时间：
2022-11
影响因子：
3.6
通讯作者：
Mingzhe Rong
中科院分区：
文献类型：
--
作者：
Jishen Zhang;Shengduo Xu;Xixi Jing;Dingxin Liu;Hao Zhang;Zifeng Wang;Dehui Xu;Geng Zhang;Xiaojian Yang;Xiaohua Wang;Michael G. Kong;Mingzhe Rong
As a means of applying cold atmospheric plasma (CAP), plasma-activated solutions have received extensive attention for their excellent anticancer effects. However, previous studies have focused mainly on the local injection of plasma-activated solutions for cancer treatment while ignoring the anticancer effects of intraluminal plasma-activated solution perfusion. In this paper, the anticancer effects of flowing plasma-activated saline (PAS) on human bladder cancer cell lines (J82) were studied in vitro in a microfluidic system. It is noteworthy that flowing PAS can kill cancer cells more efficiently than PAS immersion. Further experimental results show that the anticancer effects of PAS on J82 cells in the microcavity are affected by plasma irradiation time, perfusion time and liquid flow rate. Our research suggests that PAS perfusion therapy can become a controllable alternative therapy pathway in the future clinical treatment of intracavitary tumors.
登录
查看更多内容
影响因子：
12.8
作者：
Laila Patinglag;L. Melling;K. Whitehead;D. Sawtell;A. Iles;Kirsty J. Shaw
通讯作者：
Laila Patinglag;L. Melling;K. Whitehead;D. Sawtell;A. Iles;Kirsty J. Shaw
使用非热等离子体激活介质的新型腹腔内治疗可抑制卵巢癌细胞的转移潜力。
影响因子：
4.6
作者：
Nakamura K;Peng Y;Utsumi F;Tanaka H;Mizuno M;Toyokuni S;Hori M;Kikkawa F;Kajiyama H
通讯作者：
Kajiyama H
影响因子：
3.8
作者：
Collet, G.;Robert, E.;Pouvesle, J. M.
通讯作者：
Pouvesle, J. M.
影响因子：
2.7
作者：
Hasse, Sybille;Seebauer, Christian;Bekeschus, Sander
通讯作者：
Bekeschus, Sander
用于芯片实验室分析应用的微等离子体
影响因子：
13.1
作者：
Luo, Daibing;Duan, Yixiang
通讯作者：
Duan, Yixiang