Dysthymic and anxiety-related personality traits in bipolar spectrum illness.
Dysthymic and anxiety-related personality traits in bipolar spectrum illness.
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双相谱系疾病中的心境恶劣和焦虑相关的人格特征。
DOI：
10.1016/j.jad.2007.12.006
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发表时间：
2008
影响因子：
6.6
通讯作者：
R. Ramesar
中科院分区：
文献类型：
--
作者：
J. Savitz;L. van der Merwe;R. Ramesar
在一个情感正常的双相情感障碍（BPD）患者及其情感疾病和未受影响的亲属中，测量了抑郁和心境恶劣的人格特征。根据双相谱系疾病的定量遗传模型[Evans，L.，Akiskal，H.S.，小凯克体育课，McElroy，S.L.，Sadovnick，A.D.，Remick，R.A.，凯尔索，J.R.，2005.双相情感障碍患者气质的家族性：遗传谱的支持。J. Affect.混乱。85，153-168]，这些特征应该是正态分布的，双相情感障碍I（BPD I）组显示出最高的“病理”评分，而未受影响的亲属显示出最低的“病理”评分。来自47个双相情感障碍家庭的300名个体被给予一组人格问卷（孟菲斯、比萨、巴黎和圣地亚哥的气质评估;气质和性格量表;情感神经科学人格量表）以及抑郁自评量表（贝克抑郁量表）和躁狂自评量表（奥特曼躁狂自评量表）。在300名参与者中，58人被诊断为BPD I，27人患有双相情感障碍II（BPD II），58人患有复发性重性抑郁症（MDE-R），45人有一次抑郁发作（MDE-S），88人未受影响。BPD I组在TCI和ANPS的伤害回避和悲伤量表上的得分分别显著高于其未受影响的亲属，而MDE-R样本而不是BPD样本在TEMPS-A的焦虑气质（AT）子量表上的得分显著高于未受影响的亲属。一般来说，BPD样本的平均恶劣心境人格评分最高，其次是MDE-R，MDE-S和未受影响的亲属组。然而，没有显着的个性差异，发现精神病患者群体之间。虽然心境恶劣的气质特征符合相对较好的情感疾病的定量遗传模型，焦虑特征定义的AT规模，同样突出的BPD和单相抑郁症。
Anxious and dysthymic personality traits were measured in a euthymic, familial sample of bipolar (BPD) individuals and their affectively ill and unaffected relatives. According to the quantitative genetic model of bipolar spectrum illness [Evans, L., Akiskal, H.S., Keck, Jr., P.E., McElroy, S.L., Sadovnick, A.D., Remick, R.A., Kelsoe, J.R., 2005. Familiality of temperament in bipolar disorder: support for a genetic spectrum. J. Affect. Disord. 85, 153–168], these traits should be normally distributed with the bipolar disorder I (BPD I) group showing the highest and the unaffected relatives the least “pathological” scores. Three hundred individuals from 47 bipolar disorder families were administered a battery of personality questionnaires (Temperament Evaluation of Memphis, Pisa, Paris, and San Diego; Temperament and Character Inventory; Affective Neuroscience Personality Scale) as well as a self-rating depression (Beck Depression Inventory) and mania (Altman Self-Rating Mania) scale. Out of the 300 participants, 58 were diagnosed with BPD I, 27 with bipolar disorder II (BPD II), 58 with recurrent major depression (MDE-R), 45 had one previous depressive episode (MDE-S), and 88 were unaffected. The BPD I group scored significantly higher than their unaffected relatives on the Harm Avoidance and Sadness scales of the TCI and ANPS, respectively, while the MDE-R but not the BPD samples scored significantly higher than unaffected relatives on the Anxious Temperament (AT) subscale of the TEMPS-A. In general, the mean dysthymic personality scores were highest in the BPD sample, followed by the MDE-R, MDE-S, and unaffected relative groups. Nevertheless, no significant personality differences were found between the psychiatrically-ill groups. While dysthymic temperament traits conform relatively well to the quantitative genetic model of affective illness, anxious traits as defined by the AT scale, are equally salient in BPD and unipolar depression.
影响因子：
6.6
作者：
Akiskal, HS;Mendlowicz, MV;Smith, TL
通讯作者：
Smith, TL
双相情感障碍患者的气质和性格特征以及与共病酒精中毒或焦虑症的关系。
影响因子：
4.8
作者：
Nery,FabianoG;Hatch,JohnP;Glahn,DavidC;Nicoletti,MarkA;Monkul,ESerap;Najt,Pablo;Fonseca,Manoela;Bowden,CharlesL;Cloninger,CRobert;Soares,JairC
通讯作者：
Soares,JairC