Evaluation of Colorectal Cancer Incidence Trends in the United States (2000-2014).
Evaluation of Colorectal Cancer Incidence Trends in the United States (2000-2014).
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DOI：
10.3390/jcm7020022
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发表时间：
2018-01-30
影响因子：
3.9
通讯作者：
Smith SA
中科院分区：
文献类型：
--
作者：
Ansa BE;Coughlin SS;Alema-Mensah E;Smith SA
近年来，所有种族/民族的结直肠癌（CRC）发病率都有所下降;然而，每年下降的程度因人口统计学和疾病相关特征而异，这在很大程度上是未知的。这项研究检查了2000-2014年美国诊断为CRC的患者发病率的趋势和年度百分比变化（APC）。分析了从美国国家癌症研究所的监测、流行病学和最终结果（SEER）项目获得的数据，并根据性别、种族、诊断时的年龄、疾病部位和阶段对2000年至2014年SEER 18数据库中记录的所有恶性CRC患者（N = 577，708）进行了表征。计算整个研究期间的发生率和APC。总体而言，CRC的发病率从2000年的每10万人54.5例下降至2014年的每10万人38.6例，APC =-2.66（p < 0.0001）。2008年至2011年期间，发病率下降最为显著，从每10万人46.0人降至40.7人（APC =-4.04; p < 0.0001）。男性（与女性相比;率比（RR）= 1.33）和黑人（与白人相比; RR = 1.23）的发生率较高。局限期近端结肠癌是主要的癌症。在50岁以下的人中，这一比率有所上升（每100 000人中有6.6人，APC= 1.5）。CRC的年发病率随着时间的推移而下降。然而，有必要制定和实施干预措施，进一步减少人口和疾病相关亚组之间的差距。
Colorectal cancer (CRC) incidence rates have declined in recent years for people of all races/ethnicities; however, the extent to which the decrease varies annually by demographic and disease-related characteristics is largely unknown. This study examines trends and annual percent change (APC) in the incidence among persons diagnosed with CRC in the United States of America from 2000–2014. The data obtained from the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) Program were analyzed, and all persons (N = 577,708) with malignant CRC recorded in the SEER 18 database from 2000 to 2014 were characterized according to sex, race, age at diagnosis, disease site and stage. Incidence rates and APC were calculated for the entire study period. Overall, the incidence rate of CRC decreased from 54.5 in 2000 to 38.6 per 100,000 in 2014, with APC = −2.66 (p < 0.0001). Decline in rates was most profound between 2008 and 2011 from 46.0 to 40.7 per 100,000 (APC = −4.04; p < 0.0001). Rates were higher for males (vs. females; rate ratio (RR) = 1.33) and for blacks (vs. whites; RR = 1.23). Proximal colon cancers at the localized stage were the predominant cancers. An increase in rate was observed among people younger than 50 years (6.6 per 100,000, APC= 1.5). The annual rate of CRC has decreased over time. However, the development and implementation of interventions that further reduce the disparities among demographic and disease-related subgroups are warranted.
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DOI：
10.1056/nejmoa1301969
发表时间：
2013-09-19
期刊：
The New England journal of medicine
影响因子：
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作者：
Nishihara R;Wu K;Lochhead P;Morikawa T;Liao X;Qian ZR;Inamura K;Kim SA;Kuchiba A;Yamauchi M;Imamura Y;Willett WC;Rosner BA;Fuchs CS;Giovannucci E;Ogino S;Chan AT
通讯作者：
Chan AT
影响因子：
16.9
作者：
Bailey CE;Hu CY;You YN;Bednarski BK;Rodriguez-Bigas MA;Skibber JM;Cantor SB;Chang GJ
通讯作者：
Chang GJ
DOI：
10.3390/ijerph13111126
发表时间：
2016-11-11
影响因子：
--
作者：
Ansa BE;White S;Chung Y;Smith SA
通讯作者：
Smith SA
DOI：
10.1158/1055-9965.epi-16-0834
发表时间：
2017-05
期刊：
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子：
--
作者：
May FP;Glenn BA;Crespi CM;Ponce N;Spiegel BMR;Bastani R
通讯作者：
Bastani R
影响因子：
3
作者：
Koblinski, Jenna;Jandova, Jana;Nfonsam, Valentine
通讯作者：
Nfonsam, Valentine