Myocarditis and Subclinical-Like Infection Associated With SARS-CoV-2 in Two Cats Living in the Same Household in France: A Case Report With Literature Review.
Myocarditis and Subclinical-Like Infection Associated With SARS-CoV-2 in Two Cats Living in the Same Household in France: A Case Report With Literature Review.
复制标题
DOI：
10.3389/fvets.2021.748869
复制
发表时间：
2021
影响因子：
3.2
通讯作者：
Le Poder S
中科院分区：
文献类型：
--
作者：
Chetboul V;Foulex P;Kartout K;Klein AM;Sailleau C;Dumarest M;Delaplace M;Gouilh MA;Mortier J;Le Poder S
本报告首次对SARS-CoV-2相关性心肌炎进行了临床、放射学、超声心动图和生物学描述，并对一只5岁肥胖的雄性家养短毛猫(Cat-1)进行了6个月的随访，该猫因顽固性充血性心力衰竭而出现心肌肌钙蛋白I水平高(5.24 ng/ml)，并伴有大的舌部溃疡。该动物的血清学为SARS-CoV-2阳性。另一只生活在同一家庭的猫(Cat-2)从未出现任何临床症状，但也被确认为SARS-CoV-2血清学阳性。两只猫都是SARS-CoV-2聚合酶链式反应阴性。Cat-1比Cat-2与其主人有更密切的接触，在Cat-1‘S首次发生充血性心力衰竭前4周，Cat-1与其主人有密切接触，该同事的新冠肺炎聚合酶链式反应(α(B.1.1.7)变异)阳性。Cat-1患者入院时的焦点超声心动图显示有大量的B线、胸腔积液、严重的左房扩张和功能障碍，以及与局灶性肺实变相关的肥厚型心肌病表型。怀疑是心肌炎和肺炎，导致开出了心脏药物和抗生素的处方。1个月后，Cat-1恢复正常，左心房大小和功能恢复正常，心力衰竭体征和肺部病变消失。对SARS-CoV-2相关的宠物心脏损伤与人类病理学的比较进行了广泛的文献综述。
This report provides the first clinical, radiographic, echocardiographic, and biological description of SARS-CoV-2-associated myocarditis with a 6-month follow-up in a 5-year-old obese male domestic shorthair cat (Cat-1) presented for refractory congestive heart failure, with high cardiac troponin-I level (5.24 ng/ml), and a large lingual ulcer. The animal was SARS-CoV-2 positive on serology. The other cat living in the same household (Cat-2) never showed any clinical sign but was also confirmed SARS-CoV-2 positive on serology. Both cats were SARS-CoV-2 PCR negative. Cat-1 had closer contact than Cat-2 with their owner, who had been in close contact with a coworker tested PCR positive for COVID-19 (Alpha (B.1.1.7) variant) 4 weeks before Cat-1's first episode of congestive heart failure. A focused point-of-care echocardiography at presentation revealed for Cat-1 numerous B-lines, pleural effusion, severe left atrial dilation and dysfunction, and hypertrophic cardiomyopathy phenotype associated with focal pulmonary consolidations. Both myocarditis and pneumonia were suspected, leading to the prescription of cardiac medications and antibiotics. One month later, Cat-1 recovered, with normalization of left atrial size and function, and radiographic and echocardiography disappearance of heart failure signs and pulmonary lesions. An extensive literature review of SARS-CoV-2-related cardiac injury in pets in comparison with human pathology is discussed.
登录
查看更多内容
DOI：
10.3390/v13071379
发表时间：
2021-07-15
期刊：
Viruses
影响因子：
--
作者：
Barroso-Arévalo S;Rivera B;Domínguez L;Sánchez-Vizcaíno JM
通讯作者：
Sánchez-Vizcaíno JM
DOI：
10.1007/s10096-020-04138-6
发表时间：
2021-05
期刊：
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
影响因子：
--
作者：
Beyerstedt S;Casaro EB;Rangel ÉB
通讯作者：
Rangel ÉB
DOI：
10.1038/s41379-021-00790-1
发表时间：
2021-07
期刊：
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
影响因子：
--
作者：
Bearse M;Hung YP;Krauson AJ;Bonanno L;Boyraz B;Harris CK;Helland TL;Hilburn CF;Hutchison B;Jobbagy S;Marshall MS;Shepherd DJ;Villalba JA;Delfino I;Mendez-Pena J;Chebib I;Newton-Cheh C;Stone JR
通讯作者：
Stone JR
影响因子：
1
作者：
Chetboul, V;Sampedrano, CC;Nicolle, AP
通讯作者：
Nicolle, AP
影响因子：
11.8
作者：
Barrs VR;Peiris M;Tam KWS;Law PYT;Brackman CJ;To EMW;Yu VYT;Chu DKW;Perera RAPM;Sit THC
通讯作者：
Sit THC