Circadian rhythms of somatostatin-immunoreactivity in the suprachiasmatic nucleus of the rat
Circadian rhythms of somatostatin-immunoreactivity in the suprachiasmatic nucleus of the rat
复制标题
大鼠视交叉上核生长抑素免疫反应的昼夜节律
DOI：
10.1016/0304-3940(91)90720-e
复制
发表时间：
1991
影响因子：
2.5
通讯作者：
S. Inouye
中科院分区：
文献类型：
--
作者：
K. Shinohara;Y. Isobe;J. Takeuchi;S. Inouye
用酶免疫分析法测定了大鼠视交叉上核（SCN）内生长抑素（SS）样免疫反应（LI）的24小时变化。在盲法条件下，SCN中SS-LI的浓度存在明显的昼夜节律。峰值时间出现在主观白天早期的昼夜节律时间（CT）4左右，谷值出现在主观夜晚的CT 16或20左右。光暗周期并没有改变在盲法大鼠SCN中观察到的SS-LI的昼夜节律模式。这些结果表明，存在一个内源性的昼夜节律在SS-LI在大鼠SCN，独立于环境照明周期。
Twenty-four hour patterns in somatostatin (SS)-like immunoreactivity (LI) within the suprachiasmatic nucleus (SCN) were determined by enzyme immunoassay in rats blinded by bilateral orbital enucleation or kept sighted under light-dark conditions. A remarkable circadian rhythm was found in the concentration of SS-LI in the SCN under blinded conditions. The peak time appeared at about circadian time (CT) 4 in the early subjective day and the trough at around CT 16 or 20 in the subjective night. Light-dark cycles did not alter the circadian patterns of SS-LI observed in the blinded rat SCN. These results indicate the presence of an endogenous circadian rhythm in SS-LI in the rat SCN, independent of environmental lighting cycles.
生长抑素类似物抑制培养的下丘脑细胞分泌生长抑素。
影响因子：
4.1
作者：
Peterfreund,RA;Vale,WW
通讯作者：
Vale,WW
影响因子：
56.9
作者：
PATEL, YC;AMHERDT, M;ORCI, L
通讯作者：
ORCI, L
生长抑素受体直接与 GH4C1 垂体细胞膜中的腺苷酸环化酶偶联。
影响因子：
4.8
作者：
Koch,BD;Schonbrunn,A
通讯作者：
Schonbrunn,A