The effectiveness of peer-support for people living with HIV: A systematic review and meta-analysis.
The effectiveness of peer-support for people living with HIV: A systematic review and meta-analysis.
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DOI：
10.1371/journal.pone.0252623
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发表时间：
2021
期刊：
影响因子：
3.7
通讯作者：
Øgård-Repål A
中科院分区：
文献类型：
--
作者：
Berg RC;Page S;Øgård-Repål A
让艾滋病毒感染者参与发展和提供保健服务的做法越来越受到重视。对艾滋病毒感染者的同伴支持是由一个被视为平等的人提供援助和鼓励，在自我管理其慢性健康状况方面发挥积极作用。这项系统性审查的目的是评估同伴支持对艾滋病毒感染者的影响。我们根据国际指南进行了系统评价。在对8个数据库进行系统检索后，直到2020年5月，两名评审员根据预设的纳入标准对研究进行了独立筛选。我们对随机对照试验（RCT）中的现有证据进行了偏倚风险评估和荟萃分析。每个主要结局的证据的确定性采用建议评估、开发和评价系统的分级进行评价。在筛选了219份全文后，我们纳入了20项RCT，包括来自9个不同国家的7605名基线参与者。这些研究通常具有较低的偏倚风险。具有高度证据确定性的主要结局显示了适度但上级的护理保留（12个月随访时风险比[RR] 1.07;置信区间[CI] 95% 1.02-1.12），抗逆转录病毒治疗（ART）依从性（RR 1.06; 3个月随访时CI 95% 1.01-1.10）和病毒抑制（比值比高达6.24; 6个月随访时CI 95% 1.28-30.5）。结果显示，目前大多数其他主要结果（ART启动，CD 4细胞计数，生活质量，心理健康）的证据状态是有希望的，但太不确定，无法得出确切的结论。总体而言，在改善艾滋病毒感染者的结局方面，同伴支持与常规医疗护理上级优于常规诊所随访。这是将艾滋病毒感染者与艾滋病毒护理联系起来并留住他们的一个可行和有效的办法，有助于承担现有的服务。CRD 42020173433。
The practice of involving people living with HIV in the development and provision of healthcare has gained increasing traction. Peer-support for people living with HIV is assistance and encouragement by an individual considered equal, in taking an active role in self-management of their chronic health condition. The objective of this systematic review was to assess the effects of peer-support for people living with HIV. We conducted a systematic review in accordance with international guidelines. Following systematic searches of eight databases until May 2020, two reviewers performed independent screening of studies according to preset inclusion criteria. We conducted risk of bias assessments and meta-analyses of the available evidence in randomised controlled trials (RCTs). The certainty of the evidence for each primary outcome was evaluated with the Grading of Recommendations Assessment, Development, and Evaluation system. After screening 219 full texts we included 20 RCTs comprising 7605 participants at baseline from nine different countries. The studies generally had low risk of bias. Main outcomes with high certainty of evidence showed modest, but superior retention in care (Risk Ratio [RR] 1.07; Confidence Interval [CI] 95% 1.02–1.12 at 12 months follow-up), antiretroviral therapy (ART) adherence (RR 1.06; CI 95% 1.01–1.10 at 3 months follow-up), and viral suppression (Odds Ratio up to 6.24; CI 95% 1.28–30.5 at 6 months follow-up) for peer-support participants. The results showed that the current state of evidence for most other main outcomes (ART initiation, CD4 cell count, quality of life, mental health) was promising, but too uncertain for firm conclusions. Overall, peer-support with routine medical care is superior to routine clinic follow-up in improving outcomes for people living with HIV. It is a feasible and effective approach for linking and retaining people living with HIV to HIV care, which can help shoulder existing services. CRD42020173433.
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DOI：
10.1016/j.jana.2013.01.004
发表时间：
2014-03-01
影响因子：
2
作者：
de Souza, Rebecca
通讯作者：
de Souza, Rebecca
影响因子：
3.3
作者：
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通讯作者：
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影响因子：
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作者：
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DOI：
10.1080/09540121.2012.722600
发表时间：
2013-05-01
影响因子：
1.7
作者：
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通讯作者：
Holtgrave, David