Low dose alcohol contracts the human umbilical artery in vitro.
Low dose alcohol contracts the human umbilical artery in vitro.
复制标题
低剂量酒精在体外使人脐动脉收缩。
DOI:
10.1111/j.1530-0277.1989.tb00281.x
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发表时间:
1989
期刊:
影响因子:
--
通讯作者:
Sokol,RJ
中科院分区:
文献类型:
--
作者:
Savoy-Moore,RT;Dombrowski,MP;Cheng,A;Abel,EA;Sokol,RJ
Beginning at very low concentrations (0.001 g/100 ml), alcohol elicited dose‐dependent contractions of the human umbilical artery in vitro. Additionally, 16 of the 108 arteries tested had a 5‐10‐min spasm in response to alcohol. Alcohol (0.2 91100 ml) also increased tension developed in response to all angiotensin II doses, but had no effect on serotonin‐induced contractions. These results suggest that alcohol may increase umbilicoplacental resistance in vivo, thus decreasing fetal‐placental blood flow.
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