The Minnesota Center for Twin and Family Research genome-wide association study.
The Minnesota Center for Twin and Family Research genome-wide association study.
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DOI:
10.1017/thg.2012.62
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发表时间:
2012-12
影响因子:
0.9
通讯作者:
McGue, Matt
中科院分区:
文献类型:
--
作者:
Miller, Michael B.;Basu, Saonli;Cunningham, Julie;Eskin, Eleazar;Malone, Steven M.;Oetting, William S.;Schork, Nicholas;Sul, Jae Hoon;Iacono, William G.;McGue, Matt
As part of the Genes, Environment and Development Initiative (GEDI), the Minnesota Center for Twin and Family Research (MCTFR) undertook a genome-wide association study (GWAS), which we describe here. A total of 8405 research participants, clustered in 4-member families, have been successfully genotyped on 527,829 single nucleotide polymorphism (SNP) markers using Illumina’s Human660W-Quad array. Quality control screening of samples and markers as well as SNP imputation procedures are described. We also describe methods for ancestry control and how the familial clustering of the MCTFR sample can be accounted for in the analysis using a Rapid Feasible Generalized Least Squares algorithm. The rich longitudinal MCTFR assessments provide numerous opportunities for collaboration.
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影响因子:
30.8
作者:
通讯作者:
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DOI:
10.1158/1055-9965.epi-07-2849
发表时间:
2008-07
期刊:
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子:
--
作者:
Cunningham JM;Sellers TA;Schildkraut JM;Fredericksen ZS;Vierkant RA;Kelemen LE;Gadre M;Phelan CM;Huang Y;Meyer JG;Pankratz VS;Goode EL
通讯作者:
Goode EL
影响因子:
11
作者:
通讯作者:
--
影响因子:
30.8
作者:
通讯作者:
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DOI:
10.1375/twin.12.5.489
发表时间:
2009-10
期刊:
Twin research and human genetics : the official journal of the International Society for Twin Studies
影响因子:
--
作者:
Keyes MA;Malone SM;Elkins IJ;Legrand LN;McGue M;Iacono WG
通讯作者:
Iacono WG