Multimodal phantom of liver tissue.

Multimodal phantom of liver tissue.
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肝组织的多模式幻影。

DOI:
10.1371/journal.pone.0064180
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发表时间:
2013
期刊:
影响因子:
3.7
通讯作者:
Langø T
Langø T
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Chmarra MK;Hansen R;Mårvik R;Langø T

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医学成像在患者护理中发挥着重要作用,并不断用于管理健康和疾病。为了从这一迅速发展的技术中获得最大利益,需要进一步研究。理想情况下,这项研究应该以患者安全和环境友好的方式进行;例如,在phantomy上。这项工作的目标是开发一个协议,并制造一个多模式的肝脏体模,适用于超声,计算机断层扫描和磁共振成像模式。所提出的体模由三种类型的模拟软组织组成:肝实质、肿瘤和门静脉,由六种成分制成:蜡烛凝胶、Sephadex®、琼脂糖、甘油、蒸馏水和硅胶线。整个过程是有利的,因为体模的制备是简单的,相当具有成本效益,并且相当快-大约需要2天。此外,体模的大部分部件可以重复使用,以制造一个新的体模。对比真实的患者肝脏超声图像和所开发的体模,结果表明,所开发的体模能够很好地模拟肝脏组织及其结构。
Medical imaging plays an important role in patients' care and is continuously being used in managing health and disease. To obtain the maximum benefit from this rapidly developing technology, further research is needed. Ideally, this research should be done in a patient-safe and environment-friendly manner; for example, on phantoms. The goal of this work was to develop a protocol and manufacture a multimodal liver phantom that is suitable for ultrasound, computed tomography, and magnetic resonance imaging modalities. The proposed phantom consists of three types of mimicked soft tissues: liver parenchyma, tumors, and portal veins, that are made of six ingredients: candle gel, sephadex®, agarose, glycerol, distilled water, and silicone string. The entire procedure is advantageous, since preparation of the phantom is simple, rather cost-effective, and reasonably quick – it takes around 2 days. Besides, most of the phantom's parts can be reused to manufacture a new phantom. Comparison of ultrasound images of real patient's liver and the developed phantom shows that the phantom's liver tissue and its structures are well simulated.
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发表时间: 1992-01-01
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