Engineering Polymersome Protocells.
Engineering Polymersome Protocells.
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DOI:
10.1021/jz200640x
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发表时间:
2011-07-07
期刊:
影响因子:
--
通讯作者:
Hammer DA
中科院分区:
文献类型:
--
作者:
Kamat NP;Katz JS;Hammer DA
The field of biomimicry is embracing the construction of complex assemblies that imitate both biological structure and function. Advancements in the design of these mimetics have generated a growing vision for creating an artificial or proto- cell. Polymersomes are vesicles that can be made from synthetic, biological or hybrid polymers and can be used as a model template to build cell-like structures. In this perspective, we discuss various areas where polymersomes have been used to mimic cell functions as well as areas in which the synthetic flexibility of polymersomes would make them ideal candidates for a biomembrane mimetic. Designing a polymersome that comprehensively displays the behaviors discussed herein has the potential to lead to the development of an autonomous, responsive particle that resembles the intelligence of a biological cell.
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