Engineering Polymersome Protocells.

Engineering Polymersome Protocells.
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DOI:
10.1021/jz200640x
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发表时间:
2011-07-07
期刊:
The journal of physical chemistry letters
影响因子:
--
通讯作者:
Hammer DA
Hammer DA
中科院分区:
其他
文献类型:
--
作者:
Kamat NP;Katz JS;Hammer DA

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仿生学的领域包括模仿生物结构和功能的复杂组件的构建。这些模拟物设计的进步已经产生了创造人工或原细胞的日益增长的愿景。聚合物囊泡是可以由合成、生物或混合聚合物制成的囊泡,并且可以用作模型模板来构建细胞样结构。在这个角度来看,我们讨论了聚合物囊泡已被用于模拟细胞功能的各个领域,以及聚合物囊泡的合成灵活性将使它们成为生物膜模拟物的理想候选人的领域。设计一个全面展示本文所讨论的行为的聚合物囊泡,有可能导致类似于生物细胞智能的自主反应性颗粒的发展。
The field of biomimicry is embracing the construction of complex assemblies that imitate both biological structure and function. Advancements in the design of these mimetics have generated a growing vision for creating an artificial or proto- cell. Polymersomes are vesicles that can be made from synthetic, biological or hybrid polymers and can be used as a model template to build cell-like structures. In this perspective, we discuss various areas where polymersomes have been used to mimic cell functions as well as areas in which the synthetic flexibility of polymersomes would make them ideal candidates for a biomembrane mimetic. Designing a polymersome that comprehensively displays the behaviors discussed herein has the potential to lead to the development of an autonomous, responsive particle that resembles the intelligence of a biological cell.
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