New developed cylindrical TM010 mode EPR cavity for X-band in vivo tooth dosimetry.
New developed cylindrical TM010 mode EPR cavity for X-band in vivo tooth dosimetry.
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DOI：
10.1371/journal.pone.0106587
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Ke W
中科院分区：
文献类型：
--
作者：
Junwang G;Qingquan Y;Jianbo C;Lei M;Guofu D;Guoshan Y;Ke W
EPR牙齿在体剂量测定是一种有吸引力的方法，初步分类后，意外的核事件。研制了X波段圆柱形TM 010模谐振腔，首次用于在体牙齿剂量测量，并在EPR应用中得到应用。该腔体在腔体圆柱形壁的精确位置处具有梯形测量孔，强微波磁场H1集中，弱微波电场E1分布。采用理论计算和模拟的方法对谐振腔参数进行了设计和优化。通过测量DPPH样品、牙龈模型中的完整切牙样品和恒河猴牙齿来评估洞特征。实验结果表明，该谐振腔工作在设计的工作频率下，具有较高的EPR谱灵敏度。可以将足够的调制幅度和微波功率施加到孔中。1戈伊照射的完整切牙在30 s内即可观察到明显的EPR信号，扫描时间和检测限均为最佳。通过采集受2戈伊辐照的恒河猴牙齿的EPR信号，实现了活体光谱分析。结果表明，该腔体具有较好的灵敏度，能够满足在短时间内评估显著剂量水平的要求。该腔体为X波段体内剂量学的发展提供了一个非常有潜力的选择。
EPR tooth in vivo dosimetry is an attractive approach for initial triage after unexpected nuclear events. An X-band cylindrical TM010 mode resonant cavity was developed for in vivo tooth dosimetry and used in EPR applications for the first time. The cavity had a trapezoidal measuring aperture at the exact position of the cavity’s cylindrical wall where strong microwave magnetic field H1 concentrated and weak microwave electric field E1 distributed. Theoretical calculations and simulations were used to design and optimize the cavity parameters. The cavity features were evaluated by measuring DPPH sample, intact incisor samples embed in a gum model and the rhesus monkey teeth. The results showed that the cavity worked at designed frequency and had the ability to make EPR spectroscopy in relative high sensitivity. Sufficient modulation amplitude and microwave power could be applied into the aperture. Radiation induced EPR signal could be observed remarkably from 1 Gy irradiated intact incisor within only 30 seconds, which was among the best in scan time and detection limit. The in vivo spectroscopy was also realized by acquiring the radiation induced EPR signal from teeth of rhesus monkey whose teeth was irradiated by dose of 2 Gy. The results suggested that the cavity was sensitive to meet the demand to assess doses of significant level in short time. This cavity provided a very potential option for the development of X-band in vivo dosimetry.
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影响因子：
2.2
作者：
Williams BB;Dong R;Kmiec M;Burke G;Demidenko E;Gladstone D;Nicolalde RJ;Sucheta A;Lesniewski P;Swartz HM
通讯作者：
Swartz HM
影响因子：
2
作者：
Zhumadilov, Kassym;Ivannikov, Alexander;Hoshi, Masaharu
通讯作者：
Hoshi, Masaharu
影响因子：
2.6
作者：
Williams BB;Dong R;Nicolalde RJ;Matthews TP;Gladstone DJ;Demidenko E;Zaki BI;Salikhov IK;Lesniewski PN;Swartz HM
通讯作者：
Swartz HM
影响因子：
2
作者：
Swartz, Harold M.;Burke, Greg;Schauer, David A.
通讯作者：
Schauer, David A.
影响因子：
2.2
作者：
BRADY, JM;AARESTAD, NO;SWARTZ, HM
通讯作者：
SWARTZ, HM