The combination of two‐dimensional and three‐dimensional analysis methods contributes to the understanding of glioblastoma spatial heterogeneity

The combination of two‐dimensional and three‐dimensional analysis methods contributes to the understanding of glioblastoma spatial heterogeneity
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二维和三维分析方法的结合有助于理解胶质母细胞瘤空间异质性

DOI:
10.1002/jbio.201900196
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发表时间:
2019-11
影响因子:
2.8
通讯作者:
Yawei Liu
Yawei Liu
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Runwei Yang;Jinglin Guo;Zhiying Lin;Haimin Song;Zhanpeng Feng;Yichao Ou;Mingfeng Zhou;Yaomin Li;Guozhong Yi;Ke Li;Kaishu Li;Manlan Guo;Xiran Wang;Guanglong Huang;Zhifeng Liu;Songtao Qi;Yawei Liu

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胶质母细胞瘤(glioblastoma,GBM)患者预后差的主要原因是肿瘤细胞的异质性。然而,传统的二维(2D)分析方法,如免疫组织化学和免疫荧光,揭示GB的能力有限
Heterogeneity is regarded as the major factor leading to the poor outcomes of glioblastoma (GBM) patients. However, conventional two‐dimensional (2D) analysis methods, such as immunohistochemistry and immunofluorescence, have limited capacity to reveal GB
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