Combined EEG-fMRI and tractography to visualise propagation of epileptic activity.

Combined EEG-fMRI and tractography to visualise propagation of epileptic activity.
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DOI:
10.1136/jnnp.2007.125401
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发表时间:
2008-05
期刊:
Journal of neurology, neurosurgery, and psychiatry
影响因子:
--
通讯作者:
Duncan JS
Duncan JS
中科院分区:
其他
文献类型:
--
作者:
Hamandi K;Powell HW;Laufs H;Symms MR;Barker GJ;Parker GJ;Lemieux L;Duncan JS

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在难治性颞叶癫痫患者中,脑电图功能磁共振成像显示激活与左前颞叶发作间期放电,在左颞叶,顶叶和枕叶。动态因果模型表明,神经活动的传播从颞叶的重点领域的枕叶激活。纤维束造影显示从颞叶激活部位到枕叶激活部位的连接。这证明了结合EEG-fMRI和纤维束成像来描绘癫痫活动传播途径的原理。
In a patient with refractory temporal lobe epilepsy, EEG-fMRI showed activation in association with left anterior temporal interictal discharges, in the left temporal, parietal and occipital lobes. Dynamic causal modelling suggested propagation of neural activity from the temporal focus to the area of occipital activation. Tractography showed connections from the site of temporal lobe activation to the site of occipital activation. This demonstrates the principle of combining EEG-fMRI and tractography to delineate the pathways of propagation of epileptic activity.
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