Combined ultrasonic thermal ablation with interleaved ARFI image monitoring using a single diagnostic curvilinear array: a feasibility study.

Combined ultrasonic thermal ablation with interleaved ARFI image monitoring using a single diagnostic curvilinear array: a feasibility study.
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DOI:
10.1177/016173461103300402
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发表时间:
2011-10
期刊:
影响因子:
2.3
通讯作者:
Nightingale KR
Nightingale KR
中科院分区:
工程技术4区
文献类型:
--
作者:
Bing KF;Rouze NC;Palmeri ML;Rotemberg VM;Nightingale KR

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The goal of this work is to demonstrate the feasibility of using a diagnostic ultrasound system (Siemens Antares™ and CH6-2 curvilinear array) 1) to ablate ex vivo liver with a custom M-mode sequence and 2) to monitor the resulting tissue stiffening with 2-D Acoustic Radiation Force Impulse (ARFI) imaging. Images were taken before and after ablation, as well as in 5 s intervals during the ablation sequence in order to monitor the ablation lesion formation temporally. Ablation lesions were generated at depths up to 1.5 cm from the surface of the liver and were not visible in B-mode. ARFI images showed liver stiffening with heating that corresponded to discolored regions in gross pathology. As expected, the contrast of ablation lesions in ARFI images is observed to increase with ablation lesion size. This study demonstrated the ability of a diagnostic system using custom beam sequences to localize an ablation site, heat the site to the point of irreversible damage, and monitor the formation of the ablation lesion with ARFI imaging.
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