Evaluation of regional cerebral blood flow in acute head injury by stable xenon-enhanced computerized tomography.

Evaluation of regional cerebral blood flow in acute head injury by stable xenon-enhanced computerized tomography.
复制标题

稳定氙增强计算机断层扫描评价急性颅脑损伤的局部脑血流。

DOI:
--
复制
发表时间:
1993
期刊:
Acta Neurochirurgica Supplementum
影响因子:
--
通讯作者:
J. Muizelaar
J. Muizelaar
中科院分区:
--
文献类型:
--
作者:
G. Bouma;J. Muizelaar

文献摘要

参考文献

被引文献

相似文献

头部受伤患者的局部脑血流(rCBF)测量被认为有助于了解脑外伤的脑血流动力学和确定最佳治疗。由于 133Xe 方法的局限性,迄今为止使用 133Xe 清除技术获得的大多数数据仅做出了相对贡献。最近,通过氙增强计算机断层扫描 (Xe-CT) 测量 rCBF 成为可能,这消除了 133Xe 方法固有的大多数问题。另一方面,计算错误和对氙气吸入安全性的担忧阻碍了 Xe-CT 的临床使用。然而,CT 技术的最新进展已在很大程度上消除了这些问题。严重头部损伤中的 Xe-CT CBF 测量表明,133Xe 和 Xe-CT 获得的 CBF 值之间具有良好的相关性。通过持续将这些研究与传统 CT 结合应用,可以获得与解剖损伤相关的极早期血流紊乱(受伤后 1 至 2 小时内)的信息。初步数据显示,整体和局灶性缺血的发生率比之前发现的要高。在接下来的几天里,局部缺血往往会演变成充血。
Measurement of regional cerebral blood flow (rCBF) in head-injured patients is considered useful for understanding the cerebral hemodynamics of brain trauma and for determining the optimal therapy. Most data thus far obtained with 133Xe clearance techniques have made only relative contribution, due to limitations of the 133Xe method. More recently, is has become possible to measure rCBF by xenon-enhanced computerized tomography (Xe-CT), which obviates most problems inherent to the 133Xe method. On the other hand, computational errors and concerns regarding the safety of xenon inhalation have thwarted the clinical use of Xe-CT. Recent advances in CT technology, however, have largely eliminated these problems. Xe-CT CBF measurements in severe head injury demonstrate a good correlation between CBF values obtained with 133Xe and Xe-CT. By consistently applying these studies in conjunction with conventional CT, information on very early flow derangements (within 1 to 2 hours after injury) can be obtained, in relation to anatomical lesions. Preliminary data reveal higher incidences of global and focal ischaemia than found previously. Local ischaemia tends to evolve to hyperemia in the ensuing days.
DOI: 10.3171/jns.1991.75.4.0559
发表时间: 1991-10-01
影响因子: 4.1
作者:
LIANG, BC;THORNTON, AF;GREENBERG, HS
通讯作者: GREENBERG, HS
使用稳定的氙气增强计算机断层扫描研究脑血流来确定严重头部损伤引起的脑二氧化碳血管反应性的变化。
DOI: 10.1097/00006123-199112000-00011
发表时间: 1991
期刊: Neurosurgery
影响因子: 4.8
作者:
Marion,DW;Bouma,GJ
通讯作者: Bouma,GJ
DOI: 10.3171/jns.1991.75.5.0685
发表时间: 1991-11-01
影响因子: 4.1
作者:
BOUMA, GJ;MUIZELAAR, JP;YOUNG, HF
通讯作者: YOUNG, HF
DOI: 10.1093/neurosurgery/29.cn_suppl_1.162
发表时间: 1982
期刊: Clinical neurosurgery
影响因子: --
作者:
Miller,JD
通讯作者: Miller,JD