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Investigation of the Filamin Signaling Network's Function in Cancer Progression

Investigation of the Filamin Signaling Network's Function in Cancer Progression
细丝蛋白信号网络在癌症进展中的功能研究
批准号:
207742
负责人:
Alaoui-Jamali Moulay A
金额:
$53.93万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-03-01 至 2015-03-01

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项目成果

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中文摘要
翻译
过度的细胞运动和运动特性是癌细胞扩散和侵袭远处器官的最早事件之一(称为转移形成)。侵袭性癌细胞在原发部位以外的移动和迁移是很困难的
英文摘要
Excessive cell locomotion and motile properties are among the earliest events by which cancer cells can spread and invade distant organs (referred to as metastasis formation). Invasive cancer cell's movement and migration beyond their primary sites are co
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Characterization and therapeutic implication of a novel class of PKC-theta inhibitors selectively targeting undifferentiated cancer cells expressing stem cell markers
Triple Targeted Kinase Inhibitors Capable of Inhibiting Breast Cancer Metastases
Molecular and Translational Studies of Filamin Signaling Network in Invasive Cancer
Discovery and Validation of Pharmacological Probes for Understanding Protein-Protein Interactions of Focal Adhesion Signalling in Invasive Cancer Cells
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