Simulation and optimisation of retention in ion chromatography with multi-step elution profiles

当前离子色谱（IC）的方法是有限的，因为执行多步骤洗脱和多维分离的能力没有得到充分利用。拟议的研究将大大提高可用的分离功率，从而可以快速而简单地分析极端复杂的样品。这种类型的样本出现在许多领域，包括环境、临床、法医、能源生产和食品。因此，直接处理这些样品的能力将为对澳大利亚非常重要的广泛科学提供好处。此外，拟议的研究将产生重要的新知识产权，这些知识产权可以商业化，从而进一步提供直接的国家利益。

Current methodology in ion chromatography (IC) is limited in that the ability to perform multi-step elution and multi-dimensional separations is underutilised. The proposed research will provide a huge increase in usable separation power so that samples of extreme complexity can be analysed rapidly and simply. Samples of this type occur in many fields, including environmental, clinical, forensic, energy generation and foods. The ability to directly address such samples will therefore provide benefit to a wide range of sciences of great importance to Australia. Moreover, the proposed research will lead to significant new intellectual property which can be commercialised, thereby providing further direct national benefit.