Disrupting Chemical Communication in Bacteria: A Novel and Effective Antimicrobial Strategy

由于抗生素在疾病控制中的应用越来越多，许多病原菌对现有的抗菌素产生了抗药性。与耐药细菌相关的感染在人类健康、福祉和医疗保健成本方面造成了高昂的成本。因此，显然需要开发具有新的作用机制的新的抗菌剂。通过提供当地生产的控制细菌毒力的新技术，这里提出的技术有可能为澳大利亚人民带来巨大的健康和社会福利，并为澳大利亚工业带来商业利益。

Due to increased application of antibiotics for disease control, many pathogenic bacteria have developed resistance to existing antimicrobials. The infections associated with the resistant bacteria incur a high cost in terms of human health, well being and health care costs. Thus, there is a clear need to develop new antimicrobials that have a novel mechanism of action. The technology proposed here has the potential to deliver enormous health and social welfare benefits to the Australian population as well as commercial benefits to Australian industry, through provision of new, locally produced technologies for the control of bacterial virulence.