New scaffolds for antimicrobial discovery

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This project aims to investigate the synthesis of novel glyoxylamide antimicrobial peptide mimics that have the capacity to disrupt bacterial membranes. The innovative interdisciplinary approach expects to generate new, small molecular antimicrobial mimics that possess a low propensity for developing resistance. This could allow control of the unwanted microbial activity without the use of antibiotics that select for the resistant organisms. It will provide excellent training for young researchers and lead to high quality research publications in international journals.