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Investigating LKB1-mediated inflammation as a mediator of tumour progression

Investigating LKB1-mediated inflammation as a mediator of tumour progression
研究 LKB1 介导的炎症作为肿瘤进展的介质
批准号:
368921
负责人:
Jones Russell G
金额:
$61.02万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01

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中文摘要
翻译
现在人们认识到,免疫系统在控制癌症进展中发挥着重要作用。最近在了解T细胞对肿瘤微环境的反应方面所做的工作导致了变革性的治疗--即所谓的免疫检查点块
英文摘要
It is now appreciated that the immune system plays an important role in controlling cancer progression. Recent work in understanding how T cells respond to the tumour microenvironment has led to transformative therapies - so called "immune checkpoint bloc
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会议论文
Investigating the regulation of lymphocyte function by metabolic reprogramming
  • 批准号:
    323719
  • 项目类别:
    Operating Grants
  • 资助金额:
    $54.64万
  • 财政年份:
    2015
  • 负责人:
    Jones Russell G
  • 依托单位:
Regulation of tumourigenesis and tumour cell metabolism by the energy sensor AMPK
  • 批准号:
    267445
  • 项目类别:
    Operating Grants
  • 资助金额:
    $58.09万
  • 财政年份:
    2012
  • 负责人:
    Jones Russell G
  • 依托单位:
Development of novel animal models to study the impact of metabolism on aging: Investigating the role of the AMP-activated protein kinase (AMPK)
  • 批准号:
    228752
  • 项目类别:
    Operating Grants
  • 资助金额:
    $3.61万
  • 财政年份:
    2010
  • 负责人:
    Jones Russell G
  • 依托单位:
Role of the AMP-activated protein kinase (AMPK) in stress resistance and cancer
海外基金