Identifying conditional synthetic lethal partners of the BAF complex enhanced by PARP or ATR inhibition
Identifying conditional synthetic lethal partners of the BAF complex enhanced by PARP or ATR inhibition
批准号:
428699
负责人:
Baillie Katherine E
金额:
$1.27万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-12-01 至 2020-12-01
中文摘要
“我们的基因需要严格调控,以维持细胞功能,防止细胞生长失控。这是通过大量调节蛋白的作用来实现的,当突变时会导致癌症的发展。最近,
英文摘要
"Our genes need to be tightly regulated to maintain cell function and prevent cells from growing out of control. This is achieved through the actions of a large collection of regulatory proteins, which when mutated lead to cancer development. Recently, th
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会议论文
Protein trapping for therapeutic targeting of WRN in cancers with microsatellite instability.
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批准号:459021
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项目类别:Studentship Programs
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资助金额:$7.65万
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财政年份:2021
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负责人:Baillie Katherine E
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依托单位:
海外基金