US-Australia Joint Seminar/Workshop on the Cytoskeleton: ItsFormation and Role in the Growth, Differentiation and Structure of Wool and Hair; Adelaide, Australia; Dec. 1987

该奖项将资助八位美国科学家参加一个关于细胞骨架及其在羊毛和头发生长、分化和结构中的形成和作用的研讨会。讲习班将于1987年12月7日至11日在澳大利亚阿德莱德举行。美国西北大学医学院的Robert D. Goldman博士和纽约大学医学院的Tung-Tien H. Sun博士与阿德莱德大学的George E. Rogers博士以及委员会的其他澳大利亚成员共同策划了这次研讨会。研讨会的目的是评估头发和羊毛生长作为研究主要中间纤维（IF）蛋白，特别是角蛋白的结构和功能的模型系统的使用。中间丝蛋白是所有哺乳动物细胞系统的细胞骨架系统的主要组成部分，角蛋白是所有中间丝蛋白中最具特征的。研讨会将讨论细胞质角蛋白的结构和功能，以及核基质中新描述的角蛋白样蛋白复合物，层状蛋白，以及角蛋白系统的微生物学，包括编码这些蛋白质的基因的表征和调控。讲习班的结果将是提高对所代表国家正在进行的科学活动的认识，并增加参与者之间进行合作研究的可能性。这次会议将首次汇集澳大利亚角蛋白专家和来自美国的研究人员，他们在真核细胞的细胞骨架的细胞和分子方面具有专业知识。澳大利亚政府科学部已经批准并资助了澳大利亚参与者。美国国家科学基金会发育生物学项目主任建议将这一活动列为高优先级。

This award will support the travel of eight United States scientists to a workshop on the cytoskeleton and its formation and role in the growth, differentiation and structure of wool and hair. The workshop will be held in Adelaide, Australia, December 7-11, 1987. Dr. Robert D. Goldman, Northwestern University School of Medicine, and Dr. Tung-Tien H. Sun, New York University School of Medicine, are the U.S. organizers planning the workshop with Dr. George E. Rogers, University of Adelaide, and other Australian members of the Committee. The purpose of the workshop is to assess the use of hair and wool growth as a model system for studying the structure and function of the major intermediate filament (IF) proteins, in particular the keratins. Intermediate filament proteins are major components of the cytoskeletal system of all mammalian cell systems and keratins are the most well characterized of all of the intermediate filament proteins. Discussed at the workshop will be the structure and function of the cytoplasmic keratins and the newly described complexes of keratin-like proteins within the nuclear matrix, the lamins, as well as the microbiology of the keratin system including the characterization and regulation of the genes encoding these proteins. The result of the workshop will be an increased awareness of the scientific activities going on in the countries represented and greater possibilities for collaborative research between the participants. This meeting will bring together for the first time Australian keratin experts with investigators from the U.S. having expertise on the cellular and molecular aspects of the cytoskeleton of eukaryotic cells. The Australian Government Department of Science has already approved and funded support for the Australian participants. The NSF Program Director for Developmental Biology has recommended this activity at a high priority level.