U.S.-Chile Cooperative Research in Isolation of Iron BindingProtein of Reticulocyte Coated Vesicles

该奖项支持隔离的合作研究 网织红细胞包被的铁结合蛋白 路易斯安那州的乔纳森·格拉斯 大学的Marco Tulio Nunez 智利.这两位科学家有一个长期的， 高效的协作，此外， 与两国的其他研究人员合作。 因为 格拉斯在铁代谢细胞生物学方面的专业知识， 前两项任务，开发检测方法， 一种铁结合蛋白， 在他的实验室里。预计会取得迅速进展。 努涅斯将参加这一阶段，然后采取的 分析到智利电化学的作用 铁在涂层中的迁移梯度 将研究囊泡膜。智利人有 在跨脂质双层传导方面的专业知识， 跨囊泡膜的转运， 路易斯安那州立大学。 该项目的大部分前期工作已 已经进行了。合作已经 生产力，很可能重要的数据将 生成。这将增加少量的 关于铁跨膜转运的知识， 网状细胞因为检测开发将需要 在路易斯安那州立大学的地方，工作将在智利进行， 不可能有别的办法。这将有利于大学 在智利和那里的学生，而路易斯安那州立大学的利益， 来自一位经验丰富的拉丁美洲科学家

This award supports cooperative research on Isolation of Iron Binding Protein of Reticulocyte Coated Vesicles between Jonathan Glass of Louisiana State University and Marco Tulio Nunez of the University of Chile. These two scientists have had a long and productive collaboration and in addition, interactions with other researchers in both countries. Because of Glass's expertise in cell biology of iron metabolism, the first two tasks, development of an assay to detect an iron binding protein and its isolation will take place in his laboratory. Rapid progress is expected. Nunez will participate in this phase and then take the assay to Chile where the role of electrochemical gradients on translocation of iron across coated vesicle membranes will be studied. The Chileans have expertise in conduction across lipid bilayers and transport across vesicle membranes not available at LSU. Much of the preliminary work on this project has already been carried out. The collaboration has been productive and it is likely that significant data will be generated. This will add to the small amount of knowledge about iron transport across membranes in reticulocytes. Because the assay development will take place at LSU, work will be carried on in Chile which could not otherwise. This will benefit the university in Chile and the students there while LSU benefits from an experienced Latin American scientist.