Medium Effects in Ionic Reactions

有机化学和高分子化学项目的这笔拨款支持阿拉巴马大学亨茨维尔分校S·P·麦克马纳斯和J·M·哈里斯教授共同指导的研究。本实验旨在评价有机化合物在溶液中离子反应的溶剂效应理论。由于实验室和化学工业中使用的大多数化学反应都是在溶液相进行的，因此这项工作对于最大限度地提高化学过程的产率和优化反应条件是重要的。具体地说，将通过研究具有已知溶剂化要求的反应来测试和比较Kamlet、Taft和同事的溶剂变色理论以及Swain和其他人开发的反应性的经验方法。将速率数据应用于Kamlet-Taft和Swain提出的方程，将用于评估这些方法处理各种反应类型的速率数据的成功。这将是第一个旨在评估这两种溶剂化理论的独立实验计划。

This grant in the Organic and Macromolecular Chemistry Program suppports research jointly directed by Professors S. P. McManus and J. M. Harris, at the University of Alabama at Huntsville. This experimental work is directed at evaluating theories of solvent effects on ionic reactions of organic chemicals in solution. Since the large majority of chemical reactions used in the laboratory and in the chemical industry are carried out in the solution phase, this work is important for maximizing yields of chemical processes and for optimizing reaction conditions. Specifically, the solvatochromic theory of Kamlet, Taft, and coworkers and the empirical approach to reactivity developed by Swain and others will be tested and compared by studying reactions with known solvation requirements. Application of rate data to the equations proposed by Kamlet-Taft and by Swain will be used to assess the success of these methods to treat rate data for a variety of reaction types. This will be the first independent experimental program aimed at evaluation of these two solvation theories.