Photoacoustic cellular manipulation: building from the bottom up

在这个项目中，我们提出了一种创建复杂3D打印的方法。虽然目前的方法仅限于定义外部几何形状，但这项技术也将允许内部结构的组织，并有可能在单个单元的规模上这样做。实现这一点在生物打印人体组织和添加剂制造方面具有重要的应用。这是基于利用图案化光控制的全息声场来操纵颗粒和细胞。这与目前的声学图案化方法相比，大多局限于静态的简单几何布置，并且缺乏灵活性来产生能够制造复杂结构的任意、快速变化的场。

In this project we propose an approach for creating complex 3D prints. Whereas current approaches are limited to defining the external geometry, this technology will permit the organization of the internal structure as well, with the potential to do so at the scale of individual cells. Achieving this has important applications in bioprinting human tissues and additive manufacturing. This is based on the manipulation of particles and cells using holographic acoustic fields controlled by patterned light. This is compared to current acoustic patterning approaches are mostly limited to static simple geometric arrangements and lack the flexibility to produce arbitrary, rapidly changing fields that enable the fabrication of complex structures.