High specificity nanosensors for glycobiology

本项目旨在开发用于识别和表征碳水化合物的高特异性糖传感器。这些糖传感器有望产生关于碳水化合物立体化学结构的详细信息，以及如何控制蛋白质-碳水化合物结合和其他对生化过程至关重要的相互作用。这种创新的纳米技术旨在提供一种新的能力，以了解细胞识别和抗原结合机制。预期成果是糖生物学和研究碳水化合物结构-功能关系的新工具，加强澳大利亚在纳米传感器方面的全球声誉，为生物医学科学和利用碳水化合物的许多行业提供精辟的分析技术。

This project aims to develop high specificity glycosensors for identifying and characterising carbohydrates. These glycosensors are expected to generate detailed information on carbohydrate stereochemical structure and how this controls protein-carbohydrate binding and other interactions fundamental to biochemical processes. This innovative nanotechnology aims to deliver a new capability for understanding cellular recognition and antigen binding mechanisms. The expected outcomes are new tools for glycobiology and research into carbohydrate structure-function relationships, strengthening Australia’s global reputation in nanosensors with an incisive analytical technology for biomedical sciences and the many industries utilising carbohydrates.