Picosecond Rotational Diffusion Studies Using Time-Resolved and Phase-Resolved Spectroscopy

这个项目是在分析和表面化学的一般领域和分子光谱和分离科学的子领域。在特拉华大学Mary Wirth教授的指导下，这个实验项目的重点是分子定向测量在分析化学领域的应用。该研究的总体目标是确定通过旋转扩散参数的定量测量可以获得的溶质几何信息的数量。这一目标将通过研究1)结构非常相似的溶质，例如异构体，2)怀疑在强色谱溶剂中改变构象的大多核芳烃，3)溶质与胶束和二氧化硅表面的附着，4)溶质/溶剂体系对溶剂化相互作用了解甚少。本文提出的研究将用于检验各种分子在不同溶剂中的旋转。激光将被用作探针来测量这种旋转以及这些分子与各种溶剂的相互作用。结构非常相似的分子以及由碳和氢组成的大型有机分子将用于本研究。这些研究结果可用于预测液相色谱中类似分子的分离。

This project is in the general area of Analytical and Surface Chemistry and in the subfields of molecular spectroscopy and separations science. The thrust of this experimental program,under the direction of Professor Mary Wirth of the University of Delaware, focuses on the applications of molecular reorientation measurements to the field of analytical chemistry. The overall goal of the research is to determine the amount of solute geometry information that can be obtained by quantitative measurements of rotational diffusion parameters. This goal will be achieved by studying 1) solutes that are very similar in structure to one another, e.g. isomers, 2)large polynuclear aromatic hydrocarbons suspected of changing conformation in strong chromatographic solvents, 3)solute attachment to micelles and to silica surfaces, and 4) solute/solvent systems having poorly understood solvation interactions. The research proposed here will be used to examine the rotation of various molecules in different solvents. Lasers will be used as probes to measure this rotation as well as the interaction of these molecules with the various solvents. Molecules that are very similar in structure as well as large organic molecules composed of carbon and hydrogen will be used in this study. The results of these studies may be used to predict the separation of similar molecules in liquid chromatography.