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Translational studies of environmental stressors and epigenetic effects in major depression and suicide

Translational studies of environmental stressors and epigenetic effects in major depression and suicide
环境压力源和表观遗传效应对重度抑郁症和自杀的转化研究
批准号:
184757
负责人:
Labont Benoit
金额:
$7.65万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-10-01 至 2011-10-01

项目摘要

项目成果

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中文摘要
翻译
早期生活逆境、抑郁和自杀之间的关系已经得到很好的证明。然而,介导这种关系的分子机制知之甚少。通过对大鼠的研究,我们最近对一些
英文摘要
The relationship between early life adversity, depression and suicide has been well demonstrated. However, the molecular mechanisms mediating this relationship are poorly understood. From rat studies, we have recently gained major insight into some of the
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会议论文
The molecular and functional impact of stress in the medial prefrontal cortex
  • 批准号:
    434070
  • 项目类别:
    Operating Grants
  • 资助金额:
    $76.63万
  • 财政年份:
    2020
  • 负责人:
    Labont Benoit
  • 依托单位:
Dissecting the cortico-striatal and tegmental pathways' contribution to stress response
  • 批准号:
    433940
  • 项目类别:
    Operating Grants
  • 资助金额:
    $71.89万
  • 财政年份:
    2020
  • 负责人:
    Labont Benoit
  • 依托单位:
Sex-specific functional and transcriptional contributions of the cortico-striatal and -tegmental pathways in mediating stress susceptibility and resilience
  • 批准号:
    377727
  • 项目类别:
    Operating Grants
  • 资助金额:
    $10.93万
  • 财政年份:
    2017
  • 负责人:
    Labont Benoit
  • 依托单位:
The sex-specific epigenetic impact of early versus adult life stress in animal models of stress-induced depression
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