Acquisition of a Multinuclear High-Field Fourier Transform Nuclear Magnetic Resonance Spectrometer

核磁共振波谱是化学家用来研究分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱学对于正在进行前沿研究的化学家和生物学家来说是必不可少的。波特兰州立大学化学系（主要是本科生机构）将利用化学共享仪器计划和仪器和仪器开发计划提供的这笔奖金来帮助获得高场核磁共振光谱仪。此次收购将加强化学和生物学以下领域的研究活动：1)与人工光合作用膜有关的化合物2)含氟低分子量化合物和聚合物3)高价铬氧化剂4)大气反应产物5)缺电子杂环pi体系6)光系统中氟连接的铁硫团簇I 7)铁硫小蛋白的结构8)变性研究蛋白质热力学9)利用NOE研究钙结合蛋白的结构。

Nuclear Magnetic Resonance (NMR) spectroscopy is the most powrful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectroscopy is essential to chemists and biologists who are carrying out frontier research. The Department of Chemistry at Portland State University (a Predominantly Undergraduate Institution) will use this award given by the Chemistry Shared Instrumentation Program and the Instrumentation and Instrument Development Program to help acquire a high-field NMR spectrometer. The acquisition will enhance research actvity in the following areas of chemistry and biology: 1) Compounds relevant to membranes for artificial photosynthesis 2) Fluorine-containing low molecular weight compounds and polymers 3) High valent chromium oxidants 4) Atmospheric reaction products 5) Electron deficient heterocyclic pi-systems 6) Fluorine-ligated iron-sulfur clusters in photosystem I 7) Structure of a small iron-sulfur protein 8) Protein thermodynamics probed by denaturation 9) Structure of calcium-binding proteins using NOE.