U.S.-Australia Cooperative Research: Chemical Defense Mechanisms of Marine Annelids

该奖项将支持南安普敦长岛大学的Arthur S.Goldberg博士和澳大利亚北昆士兰James Cook大学的John C.Coll博士之间的合作研究。这项研究旨在调查海洋环节动物科蠕虫中存在化学防御物质的毒性等指标。将进行化学研究，旨在分离和确定用于化学防御的这些化合物的结构。在这些研究的基础上，将探索这些化学防御对澳大利亚中部和东北部沿海水域发现的各种海洋生态系统的影响。该项目代表了澳大利亚集团及其对海洋天然产品和化学生态的兴趣，以及Goldberg在海洋驱避毒素方面的工作之间的出色合作。这是海洋环节动物科蠕虫化学及其在海洋环境中的作用的重要基础工作，并有可能分离具有有用应用的生物活性化合物。

This award will support collaborative research between Dr. Arthur S. Goldberg of Long Island University at Southampton and Dr. John C. Coll of James Cook University of North Queensland, Australia. This research is to investigate indicators, such as, toxicity, of the presence of chemical defense substances in worms of the marine annelid family. Chemical studies will be carried out aimed at isolating and determining the structures of those compounds used for chemical defense. Building on these studies, the effects of these chemical defenses on the diverse marine ecosystems found in the coastal waters of central and northeastern Australia will be explored. The project represent excellent collaboration between the Australian group and its interest in marine natural products and chemical ecology, and the Goldberg work on marine repellent toxins. This is important fundamental work in the chemistry of worms of the marine annelid family and the role they play in the marine environment, as well as having potential for isolation of bioactive compounds with useful applications.