A National Neural Circuitry Database (NCDB): Development ofa Shared Information Resource for Basic and Clinical Neuroscience

这不是一个研究项目，而是一个试图在专家之间就科学界对国家神经电路数据库(NCDB)的要求和实施达成共识的项目。该项目的主要目标是：(1)就建立新开发银行的要求和适当性确定立场；(2)确定将构成新开发银行的数据的范围和要素；(3)确定数据表示的准确格式。这一目标可使空间和解剖数据与文本和表格字母数字数据相联系，使其能够在图形和字母数字数据和信息之间方便地移动；(4)描述一个现有的或正在开发的原型或任选的计算机系统，该系统可用于数据存储，并使各种调查人员能够进行最佳的数据通信和共享；(5)说明1.2目前现有的国家数据库系统，说明数据存储、表示、检索和共享的各种配置。在描述中包括这些系统为成功建立数据库提供的任何记录的经验和潜在的陷阱；(6)概述NCDB如何在结构上得到最好的组织，以便能够有效地建立和最大限度地组织，供神经科学研究社区、临床研究人员和教育工作者使用。这应该包括对任务和目标的理想排序，以及对财政和时间需求的估计；以及(7)根据从实现这些目标中获得的经验，就NIMH、NIDA和NSF在建立NCDB方面的未来计划发展方向和政策提出建议。

This is not a research project but one which attempts to arrive at a consensus among experts regarding the requirements of the scientific community for, and implementation of a National Neural Circuitry Database (NCDB). The major objectives of this project are to: (1) Formulate a position on the requirements for and appropriateness of establishing a NCDB; (2) Define the scope and elements of data that would constitute the NCDB; (3) Define the precise format for representation of data. This goal may allow for the linkage of spatial and anatomical data with text and tabular alphanumeric data in a way that makes it possible to move easily between graphical and alphanumeric data and information; (4) Describe a prototypic or optional computer system that either currently exists, or is under development, which can be used for data storage and which will allow for optimal data communications and sharing among various investigators; (5) Describe 1.2 currently existing national database systems that illustrate various configurations for data storage, representation, retrieval and sharing. Within this description include any documented experiences that these systems can provide for the successful establishment of the database and potential pitfalls, if available; (6) Outline how the NCDB can be best organized in structure so that it can be efficiently established and maximally organized for use by the neuroscience research community clinical investigators, and educators. This should include an ideal ordering of tasks and goals with both fiscal and temporal estimates of need; and (7) Based on what is learned from fulfilling these objectives, make recommendations on the future directions and policy in program development for the NIMH, NIDA and NSF with respect to establishment of a NCDB.