Detailed Examination of Fate, Morphogenesis and Regulation in the Anterior Neural Plate and Ridge of Xenopus laevis

这项研究计划将使用荧光标记技术， 跟踪前神经板和脊中细胞的命运 非洲爪蟾 在之前的研究中，研究人员发现， Hoechst和DiI染料可以成功地用作 神经板中小细胞群的自主标记。 利用这些染料，他们能够构建一个详细的命运图， 的神经板。 这张命运图的三个方面将得到 在计划的研究中详细关注：1）细胞 与最前面的板和脊相关的运动将 2）垂体前叶的祖先将是 （3）前壁的调节能力 神经板和脊将接受详细检查。

This researcch project will use fluorescent tagging techniques to follow the fates of cells in the anterior neural plate and ridge of Xenopus laevis. In a previous study, the investigators found that the dyes Hoechst and DiI could successfully be used as autonomous markers for small groups of cells in the neural plate. With these dyes they were able to construct a detailed fate map of the neural plate. Three aspects of this fate map will receive detailed attention in the planned research: 1) The cellular movements associated with the most anterior plate and ridge will be charted; 2) The ancestry of the anterior pituitary will be clarified; and 3) The regulatory capacities of the anterior neural plate and ridge will receive detailed examination.