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Targeting microglia-synapse interactions to rescue from brain circuits elimination and cognitive dysfunction

Targeting microglia-synapse interactions to rescue from brain circuits elimination and cognitive dysfunction
针对小胶质细胞-突触相互作用来挽救脑回路消除和认知功能障碍
批准号:
333623
负责人:
Tremblay Marie-Ève
金额:
$69.48万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-09-01 至 2020-09-01

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中文摘要
翻译
过去六年的一系列发现挑战了我们对小胶质细胞(大脑的免疫细胞)的看法,显示出它们对神经元回路的经验依赖性重塑的重要但以前意想不到的贡献。在这个新生的
英文摘要
A series of discoveries spanning the last six years has challenged our view of microglia, the brain's immune cells, showing their essential but previously unexpected contribution to the experience-dependent remodeling of neuronal circuits. In this nascent
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会议论文
Investigating the outcomes of senescence on microglial physiological and immune functions: implications for viral infection and Alzheimer's disease pathology along the aging trajectory
Investigating dark microglia during normal postnatal development and following maternal immune activation
Canada Resaerch Chair - Tier 2
Canada Research Chair Tier 2
  • 批准号:
    373615
  • 项目类别:
  • 资助金额:
    $36.43万
  • 财政年份:
    2016
  • 负责人:
    Tremblay Marie-Ève
  • 依托单位:
海外基金