Properties of Geometrically Distorted Organic Compounds

有机动力学计划的这笔赠款支持 Kenneth B博士的持续工作。耶鲁大学的Wiberg。 这项调查的结果将提供新的见解 化学反应性取决于 分子结构 维伯格教授将要进行的实验 将集中在化学和物理性质的 小环碳氢化合物中未活化的碳-碳键。 新的和不寻常的小环化合物将被合成， 将用动力学和示踪剂检查它们的反应性 问题研究 光谱方法将用于研究 键角变形和取代基效应的影响， 并通过理论计算得到 关于所观察到的特性的起源的详细信息 基态物质和活性中间体的研究

This grant from the Organic Dynamics Program supports the continuing work of Dr. Kenneth B. Wiberg at Yale University. The results of this investigation will provide new insights into the ways that chemical reactivity is dependent on molecular structure. The experiments that will be carried out by Professor Wiberg will focus on the chemical and physical properties of unactivated carbon-carbon bonds in small-ring hydrocarbons. New and unusual small-ring compounds will be synthesized, and their reactivities will be examined using kinetic and tracer studies. Spectroscopic methods will be used to study the influence of bond angle deformations and substituent effects, and theoretical calculations will be employed to obtain detailed information on the origins of the observed properties for ground-state species and reactive intermediates.