Instrumentation for Iowa State University Nucleic Acid Facility

该奖项为爱荷华州立大学动物和生物化学系的成员购买各种用于生物技术研究的设备提供资金。设备包括用于检测和分析放射性标记的核酸和蛋白质的最先进的成像设备，用于染色凝胶和自射线照相的密度测定设备，用于合成和分离DNA低聚物的设备，用于数据分析的计算机工作站和其他几个项目。这些设备将被安置在新生物技术中心的核酸设施中。生物技术基础研究的进展，包括分子生物学和细胞生物学的研究，在很大程度上依赖于DNA合成器和测序仪等仪器的发展，这些仪器使耗时和困难的实验能够迅速而不费力地完成。现在，新设备将检测和分析蛋白质和核酸的速度和灵敏度提高了几个数量级。通常，这种设备被放置在一个中心位置，供大量调查人员使用，他们可以从中受益。通过该合同购买的设备正是这样一种安排。

This award provides funds to aid in the purchase of a variety of equipment items to be used for biotechnology research by members of the zoology and biochemistry departments at Iowa State University. Equipment includes a state of the art imaging device for detection and analysis of radioactively-labelled nucleic acids and proteins, a device for densitometry of stained-gels and autoradiograms, equipment for synthesis and separation of DNA oligomers, a computer workstation for data analysis and several other items. The equipment will be housed in the nucleic acid facility of the new Biotechnology Center. Advances in basic research in Biotechnology, including studies in molecular biology and cell biology, have depended heavily on the development of instrumentation such as DNA synthesizers and sequencers that permit what had been time-consuming and difficult experimentation to be accomplished rapidly and with little effort. New devices have now increased the speed and sensitivity of detection and analysis of proteins and nucleic acids by orders of magnitude. Typically such equipment is placed in a central location where it is available to a large number of investigators who can benefit from its use. Precisely such an arrangement is proposed for the equipment to be purchased through this award.