HPLC and CZE for Protein Purification Processes

新的HPLC和CZE设备不仅将为首席研究员（pi）开发新的分离技术提供基础，而且还将为交叉检查、监测和证实理论进展提供必要的分析工具。四种分离技术将被研究：毛细管区带电泳，超临界流体为基础的过程，分析色谱和置换色谱。所要求的HPLC和CZE设备将在这些项目中用于分析工作和收集模拟和设计各种工艺所需的物理化学数据。他们也将使用，有时与修改，探索新技术的发展，以提高效率的液相色谱和CZE在生物过程中的应用。

New HPLC and CZE equipment will provide not only a base from which the Principal Investigators (PIs) will develop new separation techniques, but also essential analytical tools to cross-check and monitor and corroborate theoretical advances. Four separation techniques will be studied: capillary zone electrophoresis, supercritical fluid-based processes, analytical chromatography, and displacement chromatography. The requested HPLC and CZE equipment will be used in these projects for analytical work and for collection of physico-chemical data required in simulation and design of the various processes. They will also be used, sometimes with modifications, to explore novel techniques to be developed for the enhancement of the efficiency of both liquid chromatography and CZE in bioprocess applications.