Alkane Carbonylation and Aldehyde Decarbonylation Catalyzed by Low-Valent Transition Metal Complexes

该项目由无机，生物无机和有机资助， 金属化学计划，涉及机械的基础上， 烷烃羰基化催化剂的研究进展 逆过程，醛脱羰。 几种方法 催化体系的发展将进行研究 包括基于自由基的新型光化学和热化学 系统，光化学活化的trans-carbonylchloro- 双（三甲基膦）铑（I）和其他热 铑和钌的活性化合物。 两个实验- 催化剂设计的心理和理论方法将是 利用。 %%% 温和条件下烃的选择性官能化 条件仍然是最重要的，但难以捉摸的， 现代化学的目标。 的技术影响 选择性和能量有效的烃类反应， 巨大的。 有机金属化学家最近的发现 表明某些过渡金属络合物会反应， 在温和的条件下与碳氢化合物反应。 该项目将 试图扩展这些早期的研究，以产生催化剂， 金属化烃与碳反应的循环 一氧化碳产生醛，醛可以作为前体， 还有很多其他类型的化合物

This project, funded by the Inorganic, Bioinorganic and Organo- metallic Chemistry Program, deals with the mechanistic based development of catalysts for alkane carbonylation and the reverse process, aldehyde decarbonylation. Several approaches to the development of catalytic systems will be studied including novel radical-based photochemical and thermal systems, photochemically activated trans-carbonylchloro- bis(trimethylphosphine)rhodium(I), and other thermally activated compounds of rhodium and ruthenium. Both experi- mental and theoretical approaches to catalyst design will be utilized. %%% Selective functionalization of hydrocarbons under mild conditions remains as one of the most significant, but elusive, goals of modern chemistry. The technological implications of selective, and energy-efficient reactions of hydrocarbons are enormous. Recent discoveries by organo- metallic chemists have indicated that certain transition metal complexes will react with hydrocarbons under mild conditions. This project will attempt to extend these earlier studies to generate catalytic cycles in which metallated hydrocarbons react with carbon monoxide to produce aldehydes, which can serve as precursors to a wide variety of other types of compounds.