Computer-Assisted Chemical Analysis

这个项目是在分析和表面化学的一般领域和在分析质谱的子领域。在这项为期三年的持续拨款的任期内，威尔金斯教授和他的学生将扩展和扩大傅里叶变换质谱（FTMS）应用的研究，该研究是在NSF资助CHE-8911685的支持下发起的。将研究基质辅助激光解吸（MALD）和表面诱导解离（SID）形成的分析物离子，并用FTMS进行后续表征。威尔金斯教授还将继续开发耦合气相色谱法、红外光谱法和质谱法，作为分析复杂混合物的灵敏工具。此外，他将研究超临界流体色谱（SFC）和FTMS结合技术的分析能力。这项研究继续发展强大的分析技术，适用于广泛的化学系统。

This project is in the general area of analytical and surface chemistry and in the subfield of analytical mass spectrometry. During the tenure of this three-year continuing grant, Professor Wilkins and his students will extend and expand investigations in applications of Fourier transform mass spectrometry (FTMS) that were initiated under the aegis of NSF grant CHE-8911685. Analyte ion formation by both matrix assisted laser desorption (MALD) and by surface induced dissociation (SID) for subsequent characterization by FTMS will be studied. Professor Wilkins will also continue the development of coupled gas chromatography, infrared spectrometry, and mass spectrometry as a sensitive tool for the analysis of complex mixtures. Additionally, he will investigate the analytical capabilities of the combined techniques of supercritical fluid chromatography (SFC) and FTMS. %%% This research continues the development of powerful analytical techniques that are applicable to a broad array of chemical systems.